Nafithromycin

InChIKey RLFCSBSRGRJFRO-QAOQTAGDSA-N Formula C42H62N6O11S PubChem CID 117587595 ChEMBL CHEMBL4297519

SMILES CC[C@H]1OC(=O)[C@H](C)C(=O)[C@H](C)[C@@H](O[C@@H]2O[C@H](C)C[C@H](N(C)C)[C@H]2O)[C@](C)(OC)C[C@@H](C)C(=O)[C@H](C)[C@H]2[C@H](/C(N)=N/O[C@@H](C)c3nnc(-c4ccccn4)s3)C(=O)O[C@@]21C

Structure

2D skeletal formula · rendered by chemkit from PubChem 2D coordinates.

Protein targets · 55 targets

Small ribosomal subunit protein uS2 P0A7V0 · inhibitor · Bacterial 70S ribosome inhibitor
Large ribosomal subunit protein uL4 P60723 · inhibitor · Bacterial 70S ribosome inhibitor
Small ribosomal subunit protein bS1 P0AG67 · inhibitor · Bacterial 70S ribosome inhibitor
Small ribosomal subunit protein uS10 P0A7R5 · inhibitor · Bacterial 70S ribosome inhibitor
Small ribosomal subunit protein uS11 P0A7R9 · inhibitor · Bacterial 70S ribosome inhibitor
Small ribosomal subunit protein uS12 P0A7S3 · inhibitor · Bacterial 70S ribosome inhibitor
Small ribosomal subunit protein uS13 P0A7S9 · inhibitor · Bacterial 70S ribosome inhibitor
Small ribosomal subunit protein uS14 P0AG59 · inhibitor · Bacterial 70S ribosome inhibitor
Small ribosomal subunit protein uS15 P0ADZ4 · inhibitor · Bacterial 70S ribosome inhibitor
Small ribosomal subunit protein bS16 P0A7T3 · inhibitor · Bacterial 70S ribosome inhibitor
Small ribosomal subunit protein uS17 P0AG63 · inhibitor · Bacterial 70S ribosome inhibitor
Small ribosomal subunit protein bS18 P0A7T7 · inhibitor · Bacterial 70S ribosome inhibitor
Small ribosomal subunit protein uS19 P0A7U3 · inhibitor · Bacterial 70S ribosome inhibitor
Small ribosomal subunit protein bS20 P0A7U7 · inhibitor · Bacterial 70S ribosome inhibitor
Small ribosomal subunit protein bS21 P68679 · inhibitor · Bacterial 70S ribosome inhibitor
Small ribosomal subunit protein uS3 P0A7V3 · inhibitor · Bacterial 70S ribosome inhibitor
Small ribosomal subunit protein uS4 P0A7V8 · inhibitor · Bacterial 70S ribosome inhibitor
Small ribosomal subunit protein uS5 P0A7W1 · inhibitor · Bacterial 70S ribosome inhibitor
Small ribosomal subunit protein bS6 P02358 · inhibitor · Bacterial 70S ribosome inhibitor
Small ribosomal subunit protein uS7 P02359 · inhibitor · Bacterial 70S ribosome inhibitor
Small ribosomal subunit protein uS8 P0A7W7 · inhibitor · Bacterial 70S ribosome inhibitor
Small ribosomal subunit protein uS9 P0A7X3 · inhibitor · Bacterial 70S ribosome inhibitor
Large ribosomal subunit protein uL10 P0A7J3 · inhibitor · Bacterial 70S ribosome inhibitor
Large ribosomal subunit protein uL11 P0A7J7 · inhibitor · Bacterial 70S ribosome inhibitor
Large ribosomal subunit protein uL13 P0AA10 · inhibitor · Bacterial 70S ribosome inhibitor
Large ribosomal subunit protein uL14 P0ADY3 · inhibitor · Bacterial 70S ribosome inhibitor
Large ribosomal subunit protein uL15 P02413 · inhibitor · Bacterial 70S ribosome inhibitor
Large ribosomal subunit protein uL16 P0ADY7 · inhibitor · Bacterial 70S ribosome inhibitor
Large ribosomal subunit protein bL17 P0AG44 · inhibitor · Bacterial 70S ribosome inhibitor
Large ribosomal subunit protein uL18 P0C018 · inhibitor · Bacterial 70S ribosome inhibitor
Large ribosomal subunit protein bL19 P0A7K6 · inhibitor · Bacterial 70S ribosome inhibitor
Large ribosomal subunit protein uL1 P0A7L0 · inhibitor · Bacterial 70S ribosome inhibitor
Large ribosomal subunit protein bL20 P0A7L3 · inhibitor · Bacterial 70S ribosome inhibitor
Large ribosomal subunit protein bL21 P0AG48 · inhibitor · Bacterial 70S ribosome inhibitor
Large ribosomal subunit protein uL22 P61175 · inhibitor · Bacterial 70S ribosome inhibitor
Large ribosomal subunit protein uL23 P0ADZ0 · inhibitor · Bacterial 70S ribosome inhibitor
Large ribosomal subunit protein uL24 P60624 · inhibitor · Bacterial 70S ribosome inhibitor
Large ribosomal subunit protein bL25 P68919 · inhibitor · Bacterial 70S ribosome inhibitor
Large ribosomal subunit protein bL27 P0A7L8 · inhibitor · Bacterial 70S ribosome inhibitor
Large ribosomal subunit protein bL28 P0A7M2 · inhibitor · Bacterial 70S ribosome inhibitor
Large ribosomal subunit protein uL29 P0A7M6 · inhibitor · Bacterial 70S ribosome inhibitor
Large ribosomal subunit protein uL2 P60422 · inhibitor · Bacterial 70S ribosome inhibitor
Large ribosomal subunit protein uL30 P0AG51 · inhibitor · Bacterial 70S ribosome inhibitor
Large ribosomal subunit protein bL31B P0A7N1 · inhibitor · Bacterial 70S ribosome inhibitor
Large ribosomal subunit protein bL31 P0A7M9 · inhibitor · Bacterial 70S ribosome inhibitor
Large ribosomal subunit protein bL32 P0A7N4 · inhibitor · Bacterial 70S ribosome inhibitor
Large ribosomal subunit protein bL33 P0A7N9 · inhibitor · Bacterial 70S ribosome inhibitor
Large ribosomal subunit protein bL34 P0A7P5 · inhibitor · Bacterial 70S ribosome inhibitor
Large ribosomal subunit protein bL35 P0A7Q1 · inhibitor · Bacterial 70S ribosome inhibitor
Large ribosomal subunit protein bL36B Q2EEQ2 · inhibitor · Bacterial 70S ribosome inhibitor
Large ribosomal subunit protein bL36A P0A7Q6 · inhibitor · Bacterial 70S ribosome inhibitor
Large ribosomal subunit protein uL3 P60438 · inhibitor · Bacterial 70S ribosome inhibitor
Large ribosomal subunit protein uL5 P62399 · inhibitor · Bacterial 70S ribosome inhibitor
Large ribosomal subunit protein uL6 P0AG55 · inhibitor · Bacterial 70S ribosome inhibitor
Large ribosomal subunit protein bL12 P0A7K2 · inhibitor · Bacterial 70S ribosome inhibitor

Each resolved target links to its lmmol protein document; action and mechanism are from the bioactivity record.

A document in the lmmol reference corpus — a real compound (PubChem / ChEMBL identity, chemkit-rendered structure) cross-linked to the protein documents it targets. Hover any link to preview its target.