Oprozomib
SMILES COC[C@H](NC(=O)c1cnc(C)s1)C(=O)N[C@@H](COC)C(=O)N[C@@H](Cc1ccccc1)C(=O)[C@@]1(C)CO1
Structure
2D skeletal formula · rendered by chemkit from PubChem 2D coordinates.
Protein targets · 38 targets
- 26S proteasome non-ATPase regulatory subunit 1 Q99460 · inhibitor · 26S proteasome inhibitor
- Proteasome subunit beta type-2 P49721 · inhibitor · 26S proteasome inhibitor
- Proteasome subunit beta type-1 P20618 · inhibitor · 26S proteasome inhibitor
- Proteasome subunit beta type-5 P28074 · inhibitor · 26S proteasome inhibitor
- Proteasome subunit beta type-8 P28062 · inhibitor · 26S proteasome inhibitor
- Proteasome subunit beta type-9 P28065 · inhibitor · 26S proteasome inhibitor
- Proteasome subunit beta type-6 P28072 · inhibitor · 26S proteasome inhibitor
- Ubiquitin C-terminal hydrolase PSMD14 O00487 · inhibitor · 26S proteasome inhibitor
- Proteasome subunit alpha type-1 P25786 · inhibitor · 26S proteasome inhibitor
- Proteasome subunit alpha type-2 P25787 · inhibitor · 26S proteasome inhibitor
- Proteasome subunit alpha type-3 P25788 · inhibitor · 26S proteasome inhibitor
- Proteasome subunit alpha type-4 P25789 · inhibitor · 26S proteasome inhibitor
- Proteasome subunit alpha type-5 P28066 · inhibitor · 26S proteasome inhibitor
- Proteasome subunit alpha type-6 P60900 · inhibitor · 26S proteasome inhibitor
- Proteasome subunit alpha type-7 O14818 · inhibitor · 26S proteasome inhibitor
- Proteasome subunit alpha-type 8 Q8TAA3 · inhibitor · 26S proteasome inhibitor
- Proteasome subunit beta type-10 P40306 · inhibitor · 26S proteasome inhibitor
- Proteasome subunit beta type-11 A5LHX3 · inhibitor · 26S proteasome inhibitor
- Proteasome subunit beta type-3 P49720 · inhibitor · 26S proteasome inhibitor
- Proteasome subunit beta type-4 P28070 · inhibitor · 26S proteasome inhibitor
- Proteasome subunit beta type-7 Q99436 · inhibitor · 26S proteasome inhibitor
- Proteasomal ubiquitin receptor ADRM1 Q16186 · inhibitor · 26S proteasome inhibitor
- 26S proteasome regulatory subunit 7 P35998 · inhibitor · 26S proteasome inhibitor
- 26S proteasome regulatory subunit 4 P62191 · inhibitor · 26S proteasome inhibitor
- 26S proteasome regulatory subunit 6B P43686 · inhibitor · 26S proteasome inhibitor
- 26S proteasome regulatory subunit 10B P62333 · inhibitor · 26S proteasome inhibitor
- 26S proteasome regulatory subunit 6A P17980 · inhibitor · 26S proteasome inhibitor
- 26S proteasome regulatory subunit 8 P62195 · inhibitor · 26S proteasome inhibitor
- 26S proteasome non-ATPase regulatory subunit 2 Q13200 · inhibitor · 26S proteasome inhibitor
- 26S proteasome non-ATPase regulatory subunit 3 O43242 · inhibitor · 26S proteasome inhibitor
- 26S proteasome non-ATPase regulatory subunit 12 O00232 · inhibitor · 26S proteasome inhibitor
- 26S proteasome non-ATPase regulatory subunit 11 O00231 · inhibitor · 26S proteasome inhibitor
- 26S proteasome non-ATPase regulatory subunit 6 Q15008 · inhibitor · 26S proteasome inhibitor
- 26S proteasome non-ATPase regulatory subunit 7 P51665 · inhibitor · 26S proteasome inhibitor
- 26S proteasome non-ATPase regulatory subunit 13 Q9UNM6 · inhibitor · 26S proteasome inhibitor
- 26S proteasome non-ATPase regulatory subunit 4 P55036 · inhibitor · 26S proteasome inhibitor
- 26S proteasome non-ATPase regulatory subunit 8 P48556 · inhibitor · 26S proteasome inhibitor
- 26S proteasome complex subunit SEM1 P60896 · inhibitor · 26S proteasome inhibitor
Each resolved target links to its lmmol protein document; action and mechanism are from the bioactivity record.
A document in the lmmol reference corpus — a real compound (PubChem / ChEMBL identity, chemkit-rendered structure) cross-linked to the protein documents it targets. Hover any link to preview its target.