Topiramate
SMILES CC1(C)O[C@@H]2[C@@H](CO[C@@]3(COS(N)(=O)=O)OC(C)(C)O[C@@H]23)O1
Structure
2D skeletal formula · rendered by chemkit from PubChem 2D coordinates.
Pseudo-3D ball-and-stick · chemkit, from PubChem 3D conformer coordinates.
Protein targets · 37 targets
- Carbonic anhydrase 2 P00918 · inhibitor · Carbonic anhydrase II inhibitor
- Carbonic anhydrase 4 P22748 · inhibitor · Carbonic anhydrase IV inhibitor
- Glutamate receptor 4 P48058 · antagonist · Glutamate receptor ionotropic AMPA antagonist
- Glutamate receptor 3 P42263 · antagonist · Glutamate receptor ionotropic AMPA antagonist
- Glutamate receptor 2 P42262 · antagonist · Glutamate receptor ionotropic AMPA antagonist
- Glutamate receptor 1 P42261 · antagonist · Glutamate receptor ionotropic AMPA antagonist
- Glutamate receptor ionotropic, kainate 1 P39086 · antagonist · Glutamate receptor ionotropic kainate antagonist
- Glutamate receptor ionotropic, kainate 5 Q16478 · antagonist · Glutamate receptor ionotropic kainate antagonist
- Glutamate receptor ionotropic, kainate 4 Q16099 · antagonist · Glutamate receptor ionotropic kainate antagonist
- Glutamate receptor ionotropic, kainate 2 Q13002 · antagonist · Glutamate receptor ionotropic kainate antagonist
- Glutamate receptor ionotropic, kainate 3 Q13003 · antagonist · Glutamate receptor ionotropic kainate antagonist
- Gamma-aminobutyric acid receptor subunit alpha-1 P14867 · positive modulator · GABA-A receptor; anion channel positive modulator
- Gamma-aminobutyric acid receptor subunit beta-2 P47870 · positive modulator · GABA-A receptor; anion channel positive modulator
- Gamma-aminobutyric acid receptor subunit gamma-2 P18507 · positive modulator · GABA-A receptor; anion channel positive modulator
- Gamma-aminobutyric acid receptor subunit beta-3 P28472 · positive modulator · GABA-A receptor; anion channel positive modulator
- Gamma-aminobutyric acid receptor subunit alpha-4 P48169 · positive modulator · GABA-A receptor; anion channel positive modulator
- Gamma-aminobutyric acid receptor subunit gamma-3 Q99928 · positive modulator · GABA-A receptor; anion channel positive modulator
- Gamma-aminobutyric acid receptor subunit theta Q9UN88 · positive modulator · GABA-A receptor; anion channel positive modulator
- Gamma-aminobutyric acid receptor subunit alpha-3 P34903 · positive modulator · GABA-A receptor; anion channel positive modulator
- Gamma-aminobutyric acid receptor subunit pi O00591 · positive modulator · GABA-A receptor; anion channel positive modulator
- Gamma-aminobutyric acid receptor subunit delta O14764 · positive modulator · GABA-A receptor; anion channel positive modulator
- Gamma-aminobutyric acid receptor subunit gamma-1 Q8N1C3 · positive modulator · GABA-A receptor; anion channel positive modulator
- Gamma-aminobutyric acid receptor subunit beta-1 P18505 · positive modulator · GABA-A receptor; anion channel positive modulator
- Gamma-aminobutyric acid receptor subunit epsilon P78334 · positive modulator · GABA-A receptor; anion channel positive modulator
- Gamma-aminobutyric acid receptor subunit alpha-2 P47869 · positive modulator · GABA-A receptor; anion channel positive modulator
- Gamma-aminobutyric acid receptor subunit alpha-5 P31644 · positive modulator · GABA-A receptor; anion channel positive modulator
- Gamma-aminobutyric acid receptor subunit alpha-6 Q16445 · positive modulator · GABA-A receptor; anion channel positive modulator
- Sodium channel protein type 1 subunit alpha P35498 · blocker · Sodium channel alpha subunit blocker
- Sodium channel protein type 5 subunit alpha Q14524 · blocker · Sodium channel alpha subunit blocker
- Sodium channel protein type 4 subunit alpha P35499 · blocker · Sodium channel alpha subunit blocker
- Sodium channel protein type 7 subunit alpha Q01118 · blocker · Sodium channel alpha subunit blocker
- Sodium channel protein type 2 subunit alpha Q99250 · blocker · Sodium channel alpha subunit blocker
- Sodium channel protein type 9 subunit alpha Q15858 · blocker · Sodium channel alpha subunit blocker
- Sodium channel protein type 3 subunit alpha Q9NY46 · blocker · Sodium channel alpha subunit blocker
- Sodium channel protein type 11 subunit alpha Q9UI33 · blocker · Sodium channel alpha subunit blocker
- Sodium channel protein type 8 subunit alpha Q9UQD0 · blocker · Sodium channel alpha subunit blocker
- Sodium channel protein type 10 subunit alpha Q9Y5Y9 · blocker · Sodium channel alpha subunit blocker
Each resolved target links to its lmmol protein document; action and mechanism are from the bioactivity record.
A document in the lmmol reference corpus — a real compound (PubChem / ChEMBL identity, chemkit-rendered structure) cross-linked to the protein documents it targets. Hover any link to preview its target.