Metformin Hydrochloride

InChIKey OETHQSJEHLVLGH-UHFFFAOYSA-N Formula C4H12ClN5 PubChem CID 14219 ChEMBL CHEMBL1703

SMILES CN(C)C(=N)NC(=N)N.Cl

Structure

2D skeletal formula · rendered by chemkit from PubChem 2D coordinates.

Protein targets · 51 targets

NADH-ubiquinone oxidoreductase chain 6 P03923 · inhibitor · Mitochondrial complex I (NADH dehydrogenase) inhibitor
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial O95299 · inhibitor · Mitochondrial complex I (NADH dehydrogenase) inhibitor
NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial O00217 · inhibitor · Mitochondrial complex I (NADH dehydrogenase) inhibitor
NADH-ubiquinone oxidoreductase chain 4L P03901 · inhibitor · Mitochondrial complex I (NADH dehydrogenase) inhibitor
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 P56556 · inhibitor · Mitochondrial complex I (NADH dehydrogenase) inhibitor
NADH-ubiquinone oxidoreductase chain 1 P03886 · inhibitor · Mitochondrial complex I (NADH dehydrogenase) inhibitor
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6 O95139 · inhibitor · Mitochondrial complex I (NADH dehydrogenase) inhibitor
Cytochrome c oxidase subunit FA4 O00483 · inhibitor · Mitochondrial complex I (NADH dehydrogenase) inhibitor
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11 Q86Y39 · inhibitor · Mitochondrial complex I (NADH dehydrogenase) inhibitor
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 P17568 · inhibitor · Mitochondrial complex I (NADH dehydrogenase) inhibitor
NADH-ubiquinone oxidoreductase chain 2 P03891 · inhibitor · Mitochondrial complex I (NADH dehydrogenase) inhibitor
NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial O75306 · inhibitor · Mitochondrial complex I (NADH dehydrogenase) inhibitor
NADH-ubiquinone oxidoreductase chain 5 P03915 · inhibitor · Mitochondrial complex I (NADH dehydrogenase) inhibitor
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 P51970 · inhibitor · Mitochondrial complex I (NADH dehydrogenase) inhibitor
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial O43674 · inhibitor · Mitochondrial complex I (NADH dehydrogenase) inhibitor
NADH-ubiquinone oxidoreductase chain 4 P03905 · inhibitor · Mitochondrial complex I (NADH dehydrogenase) inhibitor
NADH-ubiquinone oxidoreductase chain 3 P03897 · inhibitor · Mitochondrial complex I (NADH dehydrogenase) inhibitor
Acyl carrier protein, mitochondrial O14561 · inhibitor · Mitochondrial complex I (NADH dehydrogenase) inhibitor
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 O15239 · inhibitor · Mitochondrial complex I (NADH dehydrogenase) inhibitor
NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial O43181 · inhibitor · Mitochondrial complex I (NADH dehydrogenase) inhibitor
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 O43676 · inhibitor · Mitochondrial complex I (NADH dehydrogenase) inhibitor
NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial O43677 · inhibitor · Mitochondrial complex I (NADH dehydrogenase) inhibitor
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 O43678 · inhibitor · Mitochondrial complex I (NADH dehydrogenase) inhibitor
NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 O43920 · inhibitor · Mitochondrial complex I (NADH dehydrogenase) inhibitor
NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial O75251 · inhibitor · Mitochondrial complex I (NADH dehydrogenase) inhibitor
NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial O75380 · inhibitor · Mitochondrial complex I (NADH dehydrogenase) inhibitor
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1 O75438 · inhibitor · Mitochondrial complex I (NADH dehydrogenase) inhibitor
NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial O75489 · inhibitor · Mitochondrial complex I (NADH dehydrogenase) inhibitor
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3 O95167 · inhibitor · Mitochondrial complex I (NADH dehydrogenase) inhibitor
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 O95168 · inhibitor · Mitochondrial complex I (NADH dehydrogenase) inhibitor
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrial O95169 · inhibitor · Mitochondrial complex I (NADH dehydrogenase) inhibitor
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrial O95178 · inhibitor · Mitochondrial complex I (NADH dehydrogenase) inhibitor
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 O95182 · inhibitor · Mitochondrial complex I (NADH dehydrogenase) inhibitor
NADH dehydrogenase [ubiquinone] 1 subunit C2 O95298 · inhibitor · Mitochondrial complex I (NADH dehydrogenase) inhibitor
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 O96000 · inhibitor · Mitochondrial complex I (NADH dehydrogenase) inhibitor
NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial P19404 · inhibitor · Mitochondrial complex I (NADH dehydrogenase) inhibitor
NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial P28331 · inhibitor · Mitochondrial complex I (NADH dehydrogenase) inhibitor
NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial P49821 · inhibitor · Mitochondrial complex I (NADH dehydrogenase) inhibitor
NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial P56181 · inhibitor · Mitochondrial complex I (NADH dehydrogenase) inhibitor
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 Q16718 · inhibitor · Mitochondrial complex I (NADH dehydrogenase) inhibitor
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial Q16795 · inhibitor · Mitochondrial complex I (NADH dehydrogenase) inhibitor
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2 Q8N183 · inhibitor · Mitochondrial complex I (NADH dehydrogenase) inhibitor
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3 Q9BU61 · inhibitor · Mitochondrial complex I (NADH dehydrogenase) inhibitor
Cytochrome c oxidase hypoxia associated subunit FA4L2 Q9NRX3 · inhibitor · Mitochondrial complex I (NADH dehydrogenase) inhibitor
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 11, mitochondrial Q9NX14 · inhibitor · Mitochondrial complex I (NADH dehydrogenase) inhibitor
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4 Q9P032 · inhibitor · Mitochondrial complex I (NADH dehydrogenase) inhibitor
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13 Q9P0J0 · inhibitor · Mitochondrial complex I (NADH dehydrogenase) inhibitor
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 Q9UI09 · inhibitor · Mitochondrial complex I (NADH dehydrogenase) inhibitor
Complex I intermediate-associated protein 30, mitochondrial Q9Y375 · inhibitor · Mitochondrial complex I (NADH dehydrogenase) inhibitor
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 Q9Y6M9 · inhibitor · Mitochondrial complex I (NADH dehydrogenase) inhibitor
Glycerol-3-phosphate dehydrogenase, mitochondrial P43304 · inhibitor · Mitochondrial glycerol-3-phosphate dehydrogenase inhibitor

Each resolved target links to its lmmol protein document; action and mechanism are from the bioactivity record.

A document in the lmmol reference corpus — a real compound (PubChem / ChEMBL identity, chemkit-rendered structure) cross-linked to the protein documents it targets. Hover any link to preview its target.