Pentoxifylline

InChIKey BYPFEZZEUUWMEJ-UHFFFAOYSA-N Formula C13H18N4O3 PubChem CID 4740 ChEMBL CHEMBL628

SMILES CC(=O)CCCCn1c(=O)c2c(ncn2C)n(C)c1=O

Structure

2D skeletal formula · rendered by chemkit from PubChem 2D coordinates.

Pseudo-3D ball-and-stick · chemkit, from PubChem 3D conformer coordinates.

Protein targets · 25 targets

Adenosine receptor A2b P29275 · antagonist · Adenosine A2 receptor antagonist
Adenosine receptor A2a P29274 · antagonist · Adenosine A2 receptor antagonist
cGMP-specific 3',5'-cyclic phosphodiesterase O76074 · inhibitor · 3',5'-cyclic phosphodiesterase inhibitor
3',5'-cyclic-AMP phosphodiesterase 4A P27815 · inhibitor · 3',5'-cyclic phosphodiesterase inhibitor
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A Q14432 · inhibitor · 3',5'-cyclic phosphodiesterase inhibitor
Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma Q13956 · inhibitor · 3',5'-cyclic phosphodiesterase inhibitor
Rod cGMP 3',5'-cyclic phosphodiesterase subunit gamma P18545 · inhibitor · 3',5'-cyclic phosphodiesterase inhibitor
cGMP-dependent 3',5'-cyclic phosphodiesterase O00408 · inhibitor · 3',5'-cyclic phosphodiesterase inhibitor
High affinity 3',5'-cyclic-AMP phosphodiesterase 7A Q13946 · inhibitor · 3',5'-cyclic phosphodiesterase inhibitor
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A P54750 · inhibitor · 3',5'-cyclic phosphodiesterase inhibitor
High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A O76083 · inhibitor · 3',5'-cyclic phosphodiesterase inhibitor
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit beta P35913 · inhibitor · 3',5'-cyclic phosphodiesterase inhibitor
3',5'-cyclic-AMP phosphodiesterase 4D Q08499 · inhibitor · 3',5'-cyclic phosphodiesterase inhibitor
3',5'-cyclic-AMP phosphodiesterase 4B Q07343 · inhibitor · 3',5'-cyclic phosphodiesterase inhibitor
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta O43924 · inhibitor · 3',5'-cyclic phosphodiesterase inhibitor
Rod cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha P16499 · inhibitor · 3',5'-cyclic phosphodiesterase inhibitor
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B Q13370 · inhibitor · 3',5'-cyclic phosphodiesterase inhibitor
Cone cGMP-specific 3',5'-cyclic phosphodiesterase subunit alpha' P51160 · inhibitor · 3',5'-cyclic phosphodiesterase inhibitor
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B O95263 · inhibitor · 3',5'-cyclic phosphodiesterase inhibitor
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A Q9Y233 · inhibitor · 3',5'-cyclic phosphodiesterase inhibitor
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B Q01064 · inhibitor · 3',5'-cyclic phosphodiesterase inhibitor
3',5'-cyclic-AMP phosphodiesterase 4C Q08493 · inhibitor · 3',5'-cyclic phosphodiesterase inhibitor
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C Q14123 · inhibitor · 3',5'-cyclic phosphodiesterase inhibitor
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A O60658 · inhibitor · 3',5'-cyclic phosphodiesterase inhibitor
3',5'-cyclic-AMP phosphodiesterase 7B Q9NP56 · inhibitor · 3',5'-cyclic phosphodiesterase inhibitor

Each resolved target links to its lmmol protein document; action and mechanism are from the bioactivity record.

A document in the lmmol reference corpus — a real compound (PubChem / ChEMBL identity, chemkit-rendered structure) cross-linked to the protein documents it targets. Hover any link to preview its target.