Small ribosomal subunit protein uS13

Function

Component of the small ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.

Classification

Family (Pfam)

PF00416 Ribosomal_S13

InterPro

Rbsml_uS13_C, Ribosomal_uS13, Ribosomal_uS13-like_H2TH, Ribosomal_uS13_CS

Functional cluster

Archaeal Transcription & Translation Factors

Experimental structures · PDB · 174

• 4UG0 EM
• 4V6X EM 5.00A
• 5A2Q EM 3.90A
• 5AJ0 EM 3.50A
• 5FLX EM 3.90A
• 5LKS EM 3.60A
• 5OA3 EM 4.30A
• 5T2C EM 3.60A
• 5VYC X-ray 6.00A
• 6FEC EM 6.30A
• 6G18 EM 3.60A
• 6G4S EM 4.00A
• … and 162 more

A predicted model is available from AlphaFold.

Gene Ontology · 17

• GO:0005737 cytoplasm
• GO:0005829 cytosol
• GO:0022626 cytosolic ribosome
• GO:0022627 cytosolic small ribosomal subunit
• GO:0070062 extracellular exosome
• GO:0005925 focal adhesion
• GO:0016020 membrane
• GO:0005654 nucleoplasm
• GO:0005634 nucleus
• GO:0014069 postsynaptic density
• GO:0005840 ribosome
• GO:0015935 small ribosomal subunit
• GO:0003723 RNA binding
• GO:0019843 rRNA binding
• GO:0003735 structural constituent of ribosome
• GO:0002181 cytoplasmic translation
• GO:0006412 translation

Drugs targeting this protein · 2

• CYCLOHEXIMIDE inhibitor
• ATALUREN modulator

Related proteins · sequence + function similarity

• Small ribosomal subunit protein uS13 1.00
• Small ribosomal subunit protein uS13 1.00
• Small ribosomal subunit protein uS13 1.00
• Small ribosomal subunit protein uS13 1.00
• Small ribosomal subunit protein uS13 1.00
• Small ribosomal subunit protein uS13 1.00
• Small ribosomal subunit protein uS13 1.00
• Small ribosomal subunit protein uS13 1.00
• Small ribosomal subunit protein uS13 0.97
• Small ribosomal subunit protein uS13 0.96
• Small ribosomal subunit protein uS13 0.96
• Small ribosomal subunit protein uS13 0.94

Co-cited proteins · studied together in the literature

• Small ribosomal subunit protein eS24 1 shared papers
• Small ribosomal subunit protein uS15 1 shared papers
• Small ribosomal subunit protein eS25 1 shared papers
• Small ribosomal subunit protein eS8 1 shared papers
• Small ribosomal subunit protein uS19 1 shared papers
• Small ribosomal subunit protein uS9 1 shared papers
• Ubiquitin-like FUBI-ribosomal protein eS30 fusion protein 1 shared papers
• Small ribosomal subunit protein uS11 1 shared papers
• Small ribosomal subunit protein eS4, X isoform 1 shared papers
• Small ribosomal subunit protein uS7 1 shared papers
• Small ribosomal subunit protein uS17 1 shared papers
• Small ribosomal subunit protein uS8 1 shared papers

Literature · 14 cited papers

• Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation. Nat. Struct. Mol. Biol. · 2017
• N-terminome analysis of the human mitochondrial proteome. Proteomics · 2015
• A new system for naming ribosomal proteins. Curr. Opin. Struct. Biol. · 2014
• An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome. J. Proteomics · 2014
• Structures of the human and Drosophila 80S ribosome. Nature · 2013
• Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features. Mol. Cell. Proteomics · 2012
• Initial characterization of the human central proteome. BMC Syst. Biol. · 2011
• Lysine acetylation targets protein complexes and co-regulates major cellular functions. Science · 2009
• Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach. Anal. Chem. · 2009
• The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Genome Res. · 2004
• Proteomic characterization of the human centrosome by protein correlation profiling. Nature · 2003
• The DNA sequence and analysis of human chromosome 6. Nature · 2003
• … and 2 more in the literature graph