Small ribosomal subunit protein uS19

UniProt P62841 Organism Homo sapiens Gene RIG, RPS15

Also known as: RIG, RPS15

Function

Component of the small ribosomal subunit. The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell.

Classification

Family (Pfam): PF00203 Ribosomal_S19
InterPro: Ribosomal_uS19, Ribosomal_uS19_CS, Ribosomal_uS19_euk_arc, Ribosomal_uS19_SF
Functional cluster: Small-Subunit Ribosomal Proteins

Experimental structures · PDB · 171

4UG0 EM
4V6X EM 5.00A
5A2Q EM 3.90A
5AJ0 EM 3.50A
5FLX EM 3.90A
5LKS EM 3.60A
5OA3 EM 4.30A
5T2C EM 3.60A
5VYC X-ray 6.00A
6FEC EM 6.30A
6G18 EM 3.60A
6G4S EM 4.00A
… and 159 more

A predicted model is available from AlphaFold.

Gene Ontology · 23

Drugs targeting this protein · 2

CYCLOHEXIMIDE inhibitor
ATALUREN modulator

Related proteins · sequence + function similarity

Co-cited proteins · studied together in the literature

Small ribosomal subunit protein uS19 1 shared papers
Small ribosomal subunit protein uS13 1 shared papers
Small ribosomal subunit protein eS24 1 shared papers
Small ribosomal subunit protein uS15 1 shared papers
Small ribosomal subunit protein eS25 1 shared papers
Small ribosomal subunit protein eS8 1 shared papers
Small ribosomal subunit protein uS9 1 shared papers
Ubiquitin-like FUBI-ribosomal protein eS30 fusion protein 1 shared papers
Small ribosomal subunit protein uS11 1 shared papers
Small ribosomal subunit protein eS4, X isoform 1 shared papers
Small ribosomal subunit protein uS7 1 shared papers
Small ribosomal subunit protein uS17 1 shared papers

Literature · 14 cited papers

Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation. Nat. Struct. Mol. Biol. · 2017
N-terminome analysis of the human mitochondrial proteome. Proteomics · 2015
A new system for naming ribosomal proteins. Curr. Opin. Struct. Biol. · 2014
An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome. J. Proteomics · 2014
Structures of the human and Drosophila 80S ribosome. Nature · 2013
N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB. Proc. Natl. Acad. Sci. U.S.A. · 2012
Initial characterization of the human central proteome. BMC Syst. Biol. · 2011
Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach. Anal. Chem. · 2009
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Genome Res. · 2004
Proteomic characterization of the human centrosome by protein correlation profiling. Nature · 2003
Characterization of the human small-ribosomal-subunit proteins by N-terminal and internal sequencing, and mass spectrometry. Eur. J. Biochem. · 1996
Evolutionary conservation of the insulinoma gene rig and its possible function. Proc. Natl. Acad. Sci. U.S.A. · 1987
… and 2 more in the literature graph

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