Vandetanib
SMILES COc1cc2/c(=N/c3ccc(Br)cc3F)nc[nH]c2cc1OCC1CCN(C)CC1
Structure
2D skeletal formula · rendered by chemkit from PubChem 2D coordinates.
Pseudo-3D ball-and-stick · chemkit, from PubChem 3D conformer coordinates.
Protein targets · 25 targets
- Proto-oncogene tyrosine-protein kinase Src P12931 · inhibitor · Tyrosine-protein kinase SRC inhibitor
- Protein-tyrosine kinase 6 Q13882 · inhibitor · Tyrosine-protein kinase BRK inhibitor
- Angiopoietin-1 receptor Q02763 · inhibitor · Tyrosine-protein kinase TIE-2 inhibitor
- Vascular endothelial growth factor receptor 1 P17948 · inhibitor · Vascular endothelial growth factor receptor inhibitor
- Vascular endothelial growth factor receptor 3 P35916 · inhibitor · Vascular endothelial growth factor receptor inhibitor
- Vascular endothelial growth factor receptor 2 P35968 · inhibitor · Vascular endothelial growth factor receptor inhibitor
- Proto-oncogene tyrosine-protein kinase receptor Ret P07949 · inhibitor · Tyrosine-protein kinase receptor RET inhibitor
- Ephrin type-A receptor 2 P29317 · inhibitor · Ephrin receptor inhibitor
- Ephrin type-B receptor 2 P29323 · inhibitor · Ephrin receptor inhibitor
- Ephrin type-A receptor 5 P54756 · inhibitor · Ephrin receptor inhibitor
- Ephrin type-A receptor 4 P54764 · inhibitor · Ephrin receptor inhibitor
- Ephrin type-A receptor 8 P29322 · inhibitor · Ephrin receptor inhibitor
- Ephrin type-A receptor 6 Q9UF33 · inhibitor · Ephrin receptor inhibitor
- Ephrin type-A receptor 7 Q15375 · inhibitor · Ephrin receptor inhibitor
- Ephrin type-B receptor 3 P54753 · inhibitor · Ephrin receptor inhibitor
- Ephrin type-A receptor 3 P29320 · inhibitor · Ephrin receptor inhibitor
- Ephrin type-B receptor 1 P54762 · inhibitor · Ephrin receptor inhibitor
- Ephrin type-B receptor 4 P54760 · inhibitor · Ephrin receptor inhibitor
- Ephrin type-A receptor 1 P21709 · inhibitor · Ephrin receptor inhibitor
- Ephrin type-B receptor 6 O15197 · inhibitor · Ephrin receptor inhibitor
- Ephrin type-A receptor 10 Q5JZY3 · inhibitor · Ephrin receptor inhibitor
- Receptor tyrosine-protein kinase erbB-2 P04626 · inhibitor · Epidermal growth factor receptor inhibitor
- Epidermal growth factor receptor P00533 · inhibitor · Epidermal growth factor receptor inhibitor
- Receptor tyrosine-protein kinase erbB-4 Q15303 · inhibitor · Epidermal growth factor receptor inhibitor
- Receptor tyrosine-protein kinase erbB-3 P21860 · inhibitor · Epidermal growth factor receptor inhibitor
Each resolved target links to its lmmol protein document; action and mechanism are from the bioactivity record.
A document in the lmmol reference corpus — a real compound (PubChem / ChEMBL identity, chemkit-rendered structure) cross-linked to the protein documents it targets. Hover any link to preview its target.