Darigabat

InChIKey PTTQXDBPTFOCMT-UHFFFAOYSA-N Formula C22H21FN4O3S PubChem CID 76287260 ChEMBL CHEMBL3647536

SMILES CCn1cnc2c(-c3ccc(F)c(-c4ccc(S(=O)(=O)CC)cc4OC)c3)cnnc21

Structure

2D skeletal formula · rendered by chemkit from PubChem 2D coordinates.

Pseudo-3D ball-and-stick · chemkit, from PubChem 3D conformer coordinates.

Protein targets · 16 targets

Gamma-aminobutyric acid receptor subunit alpha-1 P14867 · agonist · GABA-A receptor; anion channel agonist
Gamma-aminobutyric acid receptor subunit beta-2 P47870 · agonist · GABA-A receptor; anion channel agonist
Gamma-aminobutyric acid receptor subunit gamma-2 P18507 · agonist · GABA-A receptor; anion channel agonist
Gamma-aminobutyric acid receptor subunit beta-3 P28472 · agonist · GABA-A receptor; anion channel agonist
Gamma-aminobutyric acid receptor subunit alpha-4 P48169 · agonist · GABA-A receptor; anion channel agonist
Gamma-aminobutyric acid receptor subunit gamma-3 Q99928 · agonist · GABA-A receptor; anion channel agonist
Gamma-aminobutyric acid receptor subunit theta Q9UN88 · agonist · GABA-A receptor; anion channel agonist
Gamma-aminobutyric acid receptor subunit alpha-3 P34903 · agonist · GABA-A receptor; anion channel agonist
Gamma-aminobutyric acid receptor subunit pi O00591 · agonist · GABA-A receptor; anion channel agonist
Gamma-aminobutyric acid receptor subunit delta O14764 · agonist · GABA-A receptor; anion channel agonist
Gamma-aminobutyric acid receptor subunit gamma-1 Q8N1C3 · agonist · GABA-A receptor; anion channel agonist
Gamma-aminobutyric acid receptor subunit beta-1 P18505 · agonist · GABA-A receptor; anion channel agonist
Gamma-aminobutyric acid receptor subunit epsilon P78334 · agonist · GABA-A receptor; anion channel agonist
Gamma-aminobutyric acid receptor subunit alpha-2 P47869 · agonist · GABA-A receptor; anion channel agonist
Gamma-aminobutyric acid receptor subunit alpha-5 P31644 · agonist · GABA-A receptor; anion channel agonist
Gamma-aminobutyric acid receptor subunit alpha-6 Q16445 · agonist · GABA-A receptor; anion channel agonist

Each resolved target links to its lmmol protein document; action and mechanism are from the bioactivity record.

A document in the lmmol reference corpus — a real compound (PubChem / ChEMBL identity, chemkit-rendered structure) cross-linked to the protein documents it targets. Hover any link to preview its target.