Marizomib
SMILES C[C@@]12OC(=O)[C@]1([C@@H](O)[C@@H]1C=CCCC1)NC(=O)[C@@H]2CCCl
Structure
2D skeletal formula · rendered by chemkit from PubChem 2D coordinates.
Pseudo-3D ball-and-stick · chemkit, from PubChem 3D conformer coordinates.
Protein targets · 19 targets
- Proteasome subunit beta type-2 P49721 · inhibitor · 20S proteasome inhibitor
- Proteasome subunit beta type-1 P20618 · inhibitor · 20S proteasome inhibitor
- Proteasome subunit beta type-5 P28074 · inhibitor · 20S proteasome inhibitor
- Proteasome subunit beta type-8 P28062 · inhibitor · 20S proteasome inhibitor
- Proteasome subunit beta type-9 P28065 · inhibitor · 20S proteasome inhibitor
- Proteasome subunit beta type-6 P28072 · inhibitor · 20S proteasome inhibitor
- Proteasome subunit alpha type-1 P25786 · inhibitor · 20S proteasome inhibitor
- Proteasome subunit alpha type-2 P25787 · inhibitor · 20S proteasome inhibitor
- Proteasome subunit alpha type-3 P25788 · inhibitor · 20S proteasome inhibitor
- Proteasome subunit alpha type-4 P25789 · inhibitor · 20S proteasome inhibitor
- Proteasome subunit alpha type-5 P28066 · inhibitor · 20S proteasome inhibitor
- Proteasome subunit alpha type-6 P60900 · inhibitor · 20S proteasome inhibitor
- Proteasome subunit alpha type-7 O14818 · inhibitor · 20S proteasome inhibitor
- Proteasome subunit alpha-type 8 Q8TAA3 · inhibitor · 20S proteasome inhibitor
- Proteasome subunit beta type-10 P40306 · inhibitor · 20S proteasome inhibitor
- Proteasome subunit beta type-11 A5LHX3 · inhibitor · 20S proteasome inhibitor
- Proteasome subunit beta type-3 P49720 · inhibitor · 20S proteasome inhibitor
- Proteasome subunit beta type-4 P28070 · inhibitor · 20S proteasome inhibitor
- Proteasome subunit beta type-7 Q99436 · inhibitor · 20S proteasome inhibitor
Each resolved target links to its lmmol protein document; action and mechanism are from the bioactivity record.
A document in the lmmol reference corpus — a real compound (PubChem / ChEMBL identity, chemkit-rendered structure) cross-linked to the protein documents it targets. Hover any link to preview its target.