Clofarabine
SMILES Nc1nc(Cl)nc2c1ncn2[C@@H]1O[C@H](CO)[C@@H](O)[C@@H]1F
Structure
2D skeletal formula · rendered by chemkit from PubChem 2D coordinates.
Pseudo-3D ball-and-stick · chemkit, from PubChem 3D conformer coordinates.
Protein targets · 14 targets
- Ribonucleoside-diphosphate reductase large subunit P23921 · inhibitor · Ribonucleoside-diphosphate reductase RR1 inhibitor
- Ribonucleoside-diphosphate reductase subunit M2 B Q7LG56 · inhibitor · Ribonucleoside-diphosphate reductase RR1 inhibitor
- Ribonucleoside-diphosphate reductase subunit M2 P31350 · inhibitor · Ribonucleoside-diphosphate reductase RR1 inhibitor
- DNA polymerase alpha catalytic subunit P09884 · inhibitor · DNA polymerase (alpha/delta/epsilon) inhibitor
- DNA polymerase delta subunit 4 Q9HCU8 · inhibitor · DNA polymerase (alpha/delta/epsilon) inhibitor
- DNA polymerase delta subunit 3 Q15054 · inhibitor · DNA polymerase (alpha/delta/epsilon) inhibitor
- DNA polymerase delta catalytic subunit P28340 · inhibitor · DNA polymerase (alpha/delta/epsilon) inhibitor
- DNA polymerase delta subunit 2 P49005 · inhibitor · DNA polymerase (alpha/delta/epsilon) inhibitor
- DNA polymerase epsilon catalytic subunit A Q07864 · inhibitor · DNA polymerase (alpha/delta/epsilon) inhibitor
- DNA polymerase alpha subunit B Q14181 · inhibitor · DNA polymerase (alpha/delta/epsilon) inhibitor
- DNA primase small subunit P49642 · inhibitor · DNA polymerase (alpha/delta/epsilon) inhibitor
- DNA primase large subunit P49643 · inhibitor · DNA polymerase (alpha/delta/epsilon) inhibitor
- DNA polymerase epsilon subunit 2 P56282 · inhibitor · DNA polymerase (alpha/delta/epsilon) inhibitor
- DNA polymerase epsilon subunit 3 Q9NRF9 · inhibitor · DNA polymerase (alpha/delta/epsilon) inhibitor
Each resolved target links to its lmmol protein document; action and mechanism are from the bioactivity record.
A document in the lmmol reference corpus — a real compound (PubChem / ChEMBL identity, chemkit-rendered structure) cross-linked to the protein documents it targets. Hover any link to preview its target.