Voltage-dependent calcium channel gamma-6 subunit
Also known as: CACNG6
Function
Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit.
Classification
- Family (Pfam)
- PF13903 Claudin_2
- InterPro
- PMP22/EMP/MP20/Claudin, VDCC_g6su, VDCC_gsu
- Functional cluster
- Membrane Channels & Lipid-Anchored Proteins
Gene Ontology · 7
- GO:1990454 L-type voltage-gated calcium channel complex
- GO:0005886 plasma membrane
- GO:0005891 voltage-gated calcium channel complex
- GO:0005246 calcium channel regulator activity
- GO:0005245 voltage-gated calcium channel activity
- GO:0006816 calcium ion transport
- GO:1902514 regulation of calcium ion transmembrane transport via high voltage-gated calcium channel
Drugs targeting this protein · 9
- PREGABALIN modulator
- BEPRIDIL HYDROCHLORIDE blocker
- GABAPENTIN ENACARBIL modulator
- IMAGABALIN modulator
- SULOCTIDIL blocker
- PHLOROGLUCINOL blocker
- TERODILINE HYDROCHLORIDE blocker
- ATAGABALIN modulator
- GABAPENTIN modulator
Related proteins · sequence + function similarity
- Voltage-dependent calcium channel gamma-6 subunit 0.98
- Voltage-dependent calcium channel gamma-6 subunit 0.98
- Transmembrane protein 114 0.89
- Transmembrane protein 114 0.89
- Voltage-dependent calcium channel gamma-1 subunit 0.86
- Transmembrane protein 178A 0.85
- Transmembrane protein 178A 0.85
- Transmembrane protein 178A 0.85
- Transmembrane protein 178B 0.82
- Transmembrane protein 178A 0.81
- Voltage-dependent calcium channel gamma-1 subunit 0.81
- Voltage-dependent calcium channel gamma-1 subunit 0.81
Co-cited proteins · studied together in the literature
- Voltage-dependent calcium channel gamma-7 subunit 3 shared papers
- Voltage-dependent calcium channel gamma-8 subunit 3 shared papers
- Voltage-dependent calcium channel gamma-6 subunit 2 shared papers
- Voltage-dependent calcium channel gamma-6 subunit 2 shared papers
- Voltage-dependent calcium channel gamma-8 subunit 2 shared papers
- Voltage-dependent calcium channel gamma-4 subunit 2 shared papers
- Voltage-dependent calcium channel gamma-7 subunit 2 shared papers
- Voltage-dependent L-type calcium channel subunit beta-1 1 shared papers
- Voltage-dependent calcium channel gamma-like subunit 1 shared papers
- Voltage-dependent calcium channel gamma-like subunit 1 shared papers
- Voltage-dependent L-type calcium channel subunit beta-1 1 shared papers
- Voltage-dependent calcium channel gamma-4 subunit 1 shared papers
Literature · 4 cited papers
- Cardiac L-type calcium channel (Cav1.2) associates with gamma subunits. FASEB J. · 2011
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Genome Res. · 2004
- Calcium channel gamma subunits provide insights into the evolution of this gene family. Gene · 2001
- A cluster of three novel Ca(2+) channel gamma subunit genes on chromosome 19q13.4: evolution and expression profile of the gamma subunit gene family. Genomics · 2001
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