Envelope glycoprotein J
Also known as: gJ
Function
Inhibits host cell apoptosis. Induces an increase in reactive oxygen species (ROS) in the host cell.
Classification
- Family (Pfam)
- PF03229 Alpha_GJ
- InterPro
- Herpes_gJ
- Functional cluster
- Secreted Growth Factors & Cytokines
Gene Ontology · 3
Drugs targeting this protein · 1
- DOCOSANOL inhibitor
Related proteins · sequence + function similarity
- Subgroup A Rous sarcoma virus receptor pg950 0.69
- Envelope glycoprotein N 0.69
- Small integral membrane protein 32 0.68
- Transmembrane protein 125 0.67
- Transmembrane protein 125 0.67
- Tuberoinfundibular peptide of 39 residues 0.67
- Tuberoinfundibular peptide of 39 residues 0.67
- Envelope glycoprotein J 0.67
- Transmembrane protein 253 0.66
- E3 ubiquitin-protein ligase ZNRF4 0.66
- Small integral membrane protein 41 0.66
- LRRN4 C-terminal-like protein 0.64
Co-cited proteins · studied together in the literature
- Envelope glycoprotein G 3 shared papers
- Protein US2 1 shared papers
- Protein US8.5 1 shared papers
- Envelope protein US9 2 shared papers
- Virion protein US10 1 shared papers
- Envelope glycoprotein I 2 shared papers
- Membrane protein UL43 1 shared papers
- Envelope protein UL45 1 shared papers
- Tegument protein UL21 1 shared papers
- Virion protein US10 1 shared papers
- Envelope glycoprotein E 1 shared papers
- ICP47 protein 1 shared papers
Literature · 6 cited papers
- Comprehensive characterization of extracellular herpes simplex virus type 1 virions. J. Virol. · 2008
- The antiapoptotic herpes simplex virus glycoprotein J localizes to multiple cellular organelles and induces reactive oxygen species formation. J. Virol. · 2008
- Determination and analysis of the DNA sequence of highly attenuated herpes simplex virus type 1 mutant HF10, a potential oncolytic virus. Microbes Infect. · 2007
- Patterns of Eurasian HSV-1 molecular diversity and inferences of human migrations. Infect. Genet. Evol. · 2006
- Sequence determination and genetic content of the short unique region in the genome of herpes simplex virus type 1. J. Mol. Biol. · 1985
- The complete DNA sequence of the long unique region in the genome of herpes simplex virus type 1. J. Gen. Virol. · 1988
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