Panulisib
SMILES Cn1/c(=N\C#N)n(-c2ccc(C(C)(C)C#N)nc2)c2c3cc(-c4cnc(N)c(C(F)(F)F)c4)ccc3ncc21
Structure
2D skeletal formula · rendered by chemkit from PubChem 2D coordinates.
Protein targets · 10 targets
- Phosphatidylinositol 3-kinase regulatory subunit alpha P27986 · inhibitor · PI3-kinase class I inhibitor
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform P42338 · inhibitor · PI3-kinase class I inhibitor
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform P48736 · inhibitor · PI3-kinase class I inhibitor
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform P42336 · inhibitor · PI3-kinase class I inhibitor
- Phosphatidylinositol 3-kinase regulatory subunit beta O00459 · inhibitor · PI3-kinase class I inhibitor
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform O00329 · inhibitor · PI3-kinase class I inhibitor
- Phosphoinositide 3-kinase regulatory subunit 5 Q8WYR1 · inhibitor · PI3-kinase class I inhibitor
- Phosphatidylinositol 3-kinase regulatory subunit gamma Q92569 · inhibitor · PI3-kinase class I inhibitor
- Serine/threonine-protein kinase mTOR P42345 · inhibitor · Serine/threonine-protein kinase mTOR inhibitor
- Activin receptor type-1-like P37023 · inhibitor · Serine/threonine-protein kinase receptor R3 inhibitor
Each resolved target links to its lmmol protein document; action and mechanism are from the bioactivity record.
A document in the lmmol reference corpus — a real compound (PubChem / ChEMBL identity, chemkit-rendered structure) cross-linked to the protein documents it targets. Hover any link to preview its target.