Gsk-690693
SMILES CCn1c(-c2nonc2N)nc2c(C#CC(C)(C)O)ncc(OC[C@H]3CCCNC3)c21
Structure
2D skeletal formula · rendered by chemkit from PubChem 2D coordinates.
Pseudo-3D ball-and-stick · chemkit, from PubChem 3D conformer coordinates.
Protein targets · 17 targets
- RAC-beta serine/threonine-protein kinase P31751 · inhibitor · Serine/threonine-protein kinase AKT inhibitor
- RAC-gamma serine/threonine-protein kinase Q9Y243 · inhibitor · Serine/threonine-protein kinase AKT inhibitor
- RAC-alpha serine/threonine-protein kinase P31749 · inhibitor · Serine/threonine-protein kinase AKT inhibitor
- cAMP-dependent protein kinase catalytic subunit beta P22694 · inhibitor · cAMP-dependent protein kinase (PKA) inhibitor
- cAMP-dependent protein kinase catalytic subunit alpha P17612 · inhibitor · cAMP-dependent protein kinase (PKA) inhibitor
- cAMP-dependent protein kinase catalytic subunit gamma P22612 · inhibitor · cAMP-dependent protein kinase (PKA) inhibitor
- Serine/threonine-protein kinase D3 O94806 · inhibitor · Protein kinase C (PKC) inhibitor
- Protein kinase C iota type P41743 · inhibitor · Protein kinase C (PKC) inhibitor
- Protein kinase C alpha type P17252 · inhibitor · Protein kinase C (PKC) inhibitor
- Protein kinase C gamma type P05129 · inhibitor · Protein kinase C (PKC) inhibitor
- Protein kinase C delta type Q05655 · inhibitor · Protein kinase C (PKC) inhibitor
- Protein kinase C beta type P05771 · inhibitor · Protein kinase C (PKC) inhibitor
- Protein kinase C zeta type Q05513 · inhibitor · Protein kinase C (PKC) inhibitor
- Protein kinase C epsilon type Q02156 · inhibitor · Protein kinase C (PKC) inhibitor
- Protein kinase C eta type P24723 · inhibitor · Protein kinase C (PKC) inhibitor
- Serine/threonine-protein kinase D1 Q15139 · inhibitor · Protein kinase C (PKC) inhibitor
- Protein kinase C theta type Q04759 · inhibitor · Protein kinase C (PKC) inhibitor
Each resolved target links to its lmmol protein document; action and mechanism are from the bioactivity record.
A document in the lmmol reference corpus — a real compound (PubChem / ChEMBL identity, chemkit-rendered structure) cross-linked to the protein documents it targets. Hover any link to preview its target.