Poziotinib
SMILES C=CC(=O)N1CCC(Oc2cc3c(Nc4ccc(Cl)c(Cl)c4F)ncnc3cc2OC)CC1
Structure
2D skeletal formula · rendered by chemkit from PubChem 2D coordinates.
Pseudo-3D ball-and-stick · chemkit, from PubChem 3D conformer coordinates.
Protein targets · 4 targets
- Receptor tyrosine-protein kinase erbB-2 P04626 · inhibitor · Epidermal growth factor receptor inhibitor
- Epidermal growth factor receptor P00533 · inhibitor · Epidermal growth factor receptor inhibitor
- Receptor tyrosine-protein kinase erbB-4 Q15303 · inhibitor · Epidermal growth factor receptor inhibitor
- Receptor tyrosine-protein kinase erbB-3 P21860 · inhibitor · Epidermal growth factor receptor inhibitor
Each resolved target links to its lmmol protein document; action and mechanism are from the bioactivity record.
A document in the lmmol reference corpus — a real compound (PubChem / ChEMBL identity, chemkit-rendered structure) cross-linked to the protein documents it targets. Hover any link to preview its target.