Neratinib
SMILES CCOc1cc2ncc(C#N)c(Nc3ccc(OCc4ccccn4)c(Cl)c3)c2cc1NC(=O)/C=C/CN(C)C
Structure
2D skeletal formula · rendered by chemkit from PubChem 2D coordinates.
Pseudo-3D ball-and-stick · chemkit, from PubChem 3D conformer coordinates.
Protein targets · 3 targets
- Epidermal growth factor receptor P00533 · inhibitor · Epidermal growth factor receptor erbB1 inhibitor
- Receptor tyrosine-protein kinase erbB-2 P04626 · inhibitor · Receptor protein-tyrosine kinase erbB-2 inhibitor
- Receptor tyrosine-protein kinase erbB-4 Q15303 · inhibitor · Receptor protein-tyrosine kinase erbB-4 inhibitor
Each resolved target links to its lmmol protein document; action and mechanism are from the bioactivity record.
A document in the lmmol reference corpus — a real compound (PubChem / ChEMBL identity, chemkit-rendered structure) cross-linked to the protein documents it targets. Hover any link to preview its target.