Navitoclax
SMILES CC1(C)CCC(c2ccc(Cl)cc2)=C(CN2CCN(c3ccc(C(=O)NS(=O)(=O)c4ccc(N[C@H](CCN5CCOCC5)CSc5ccccc5)c(S(=O)(=O)C(F)(F)F)c4)cc3)CC2)C1
Structure
2D skeletal formula · rendered by chemkit from PubChem 2D coordinates.
Protein targets · 3 targets
- Apoptosis regulator Bcl-2 P10415 · inhibitor · Apoptosis regulator Bcl-2 inhibitor
- Bcl-2-like protein 1 Q07817 · inhibitor · Apoptosis regulator Bcl-X inhibitor
- Bcl-2-like protein 2 Q92843 · inhibitor · Apoptosis regulator Bcl-W inhibitor
Each resolved target links to its lmmol protein document; action and mechanism are from the bioactivity record.
A document in the lmmol reference corpus — a real compound (PubChem / ChEMBL identity, chemkit-rendered structure) cross-linked to the protein documents it targets. Hover any link to preview its target.