Lotamilast
SMILES CNc1nc(-c2cccc(NC(=O)c3ccc(C(=O)OC)cc3)c2)c2cc(OC)c(OC)cc2n1
Structure
2D skeletal formula · rendered by chemkit from PubChem 2D coordinates.
Pseudo-3D ball-and-stick · chemkit, from PubChem 3D conformer coordinates.
Protein targets · 4 targets
- 3',5'-cyclic-AMP phosphodiesterase 4A P27815 · inhibitor · Phosphodiesterase 4 inhibitor
- 3',5'-cyclic-AMP phosphodiesterase 4D Q08499 · inhibitor · Phosphodiesterase 4 inhibitor
- 3',5'-cyclic-AMP phosphodiesterase 4B Q07343 · inhibitor · Phosphodiesterase 4 inhibitor
- 3',5'-cyclic-AMP phosphodiesterase 4C Q08493 · inhibitor · Phosphodiesterase 4 inhibitor
Each resolved target links to its lmmol protein document; action and mechanism are from the bioactivity record.
A document in the lmmol reference corpus — a real compound (PubChem / ChEMBL identity, chemkit-rendered structure) cross-linked to the protein documents it targets. Hover any link to preview its target.