DNA topoisomerase 4 subunit B
Also known as: PA4967, parE
Function
Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.
Classification
- Family (Pfam)
- PF00204 DNA_gyraseB, PF00986 DNA_gyraseB_C, PF02518 HATPase_c, PF01751 Toprim
- InterPro
- DNA_gyrase_B_C, HATPase_C_sf, HATPase_dom, Ribosomal_Su5_D2-typ_SF, Ribsml_uS5_D2-typ_fold_subgr, Topo_IIA, Topo_IIA-like_dom_sf, Topo_IIA_B_C, Topo_IIA_bsu_dom2, TopoIIA_CS, TopoIV_B_Gneg, TOPRIM_dom
- Functional cluster
- Ribosomal Proteins & RNA-Processing Enzymes
Gene Ontology · 8
Drugs targeting this protein · 1
- FINAFLOXACIN inhibitor
Related proteins · sequence + function similarity
- DNA topoisomerase 4 subunit B 0.91
- DNA topoisomerase 4 subunit B 0.91
- DNA topoisomerase 4 subunit B 0.90
- DNA topoisomerase 4 subunit B 0.89
- DNA gyrase subunit B 0.81
- DNA gyrase subunit B 0.78
- DNA topoisomerase 4 subunit B 0.77
- DNA gyrase subunit B 0.77
- DNA gyrase subunit B 0.77
- DNA gyrase subunit B 0.77
- DNA gyrase subunit B 0.77
- DNA topoisomerase 4 subunit B 0.76
Literature · 1 cited papers
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