Thymidylate synthase

Classification

Family (Pfam)

PF00303 Thymidylat_synt

InterPro

Thymidate_synth/dCMP_Mease, Thymidate_synth/dCMP_Mease_dom, Thymidate_synth/dCMP_Mease_sf, Thymidylate_synthase, Thymidylate_synthase_AS

Functional cluster

M20 Family Metallopeptidases

Gene Ontology · 8

• GO:0005829 cytosol
• GO:0062040 fungal biofilm matrix
• GO:0005739 mitochondrion
• GO:0034399 nuclear periphery
• GO:0004799 thymidylate synthase activity
• GO:0006231 dTMP biosynthetic process
• GO:0006235 dTTP biosynthetic process
• GO:0032259 methylation

Drugs targeting this protein · 1

• FLUCYTOSINE inhibitor

Related proteins · sequence + function similarity

• Thymidylate synthase 0.94
• Thymidylate synthase 0.93
• Thymidylate synthase 0.93
• Thymidylate synthase 0.91
• Thymidylate synthase 0.90
• Thymidylate synthase 0.90
• Thymidylate synthase 0.89
• Thymidylate synthase 0.89
• Thymidylate synthase 0.89
• Thymidylate synthase 0.89
• Thymidylate synthase 0.89
• Thymidylate synthase 0.88

Literature · 4 cited papers

• Assembly of a phased diploid Candida albicans genome facilitates allele-specific measurements and provides a simple model for repeat and indel structure. Genome Biol. · 2013
• Assembly of the Candida albicans genome into sixteen supercontigs aligned on the eight chromosomes. Genome Biol. · 2007
• The diploid genome sequence of Candida albicans. Proc. Natl. Acad. Sci. U.S.A. · 2004
• Cloning, purification, and properties of Candida albicans thymidylate synthase. J. Bacteriol. · 1989