DNA topoisomerase 4 subunit B
Also known as: grlB, parE
Function
Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule.
Classification
- Family (Pfam)
- PF00204 DNA_gyraseB, PF00986 DNA_gyraseB_C, PF02518 HATPase_c, PF01751 Toprim
- InterPro
- DNA_gyrase_B_C, HATPase_C_sf, HATPase_dom, ParE_type2, Ribosomal_Su5_D2-typ_SF, Ribsml_uS5_D2-typ_fold_subgr, Topo_IIA, Topo_IIA-like_dom_sf, Topo_IIA_B, Topo_IIA_B_C, Topo_IIA_bsu_dom2, TopoIIA_CS, TOPRIM_dom
- Functional cluster
- S-Adenosylmethionine Synthases & related
Gene Ontology · 7
Drugs targeting this protein · 2
- FINAFLOXACIN inhibitor
- OZENOXACIN inhibitor
Related proteins · sequence + function similarity
- DNA topoisomerase 4 subunit B 1.00
- DNA topoisomerase 4 subunit B 1.00
- DNA topoisomerase 4 subunit B 1.00
- DNA topoisomerase 4 subunit B 1.00
- DNA topoisomerase 4 subunit B 1.00
- DNA topoisomerase 4 subunit B 1.00
- DNA topoisomerase 4 subunit B 0.99
- DNA topoisomerase 4 subunit B 0.99
- DNA topoisomerase 4 subunit B 0.95
- DNA topoisomerase 4 subunit B 0.94
- DNA gyrase subunit B 0.91
- DNA gyrase subunit B 0.91
Co-cited proteins · studied together in the literature
- DNA topoisomerase 4 subunit A 1 shared papers
Literature · 1 cited papers
A document in the lmmol reference corpus — open public data (UniProt, GO, PDB, the literature graph) rendered as a single cross-linked page. Hover any link to preview its target.