Bardoxolone Methyl
SMILES COC(=O)[C@]12CCC(C)(C)C[C@H]1[C@H]1C(=O)C=C3[C@@]4(C)C=C(C#N)C(=O)C(C)(C)[C@@H]4CC[C@@]3(C)[C@]1(C)CC2
Structure
2D skeletal formula · rendered by chemkit from PubChem 2D coordinates.
Pseudo-3D ball-and-stick · chemkit, from PubChem 3D conformer coordinates.
Protein targets · 4 targets
- Peroxisome proliferator-activated receptor gamma P37231 · antagonist · Peroxisome proliferator-activated receptor gamma antagonist
- Inhibitor of nuclear factor kappa-B kinase subunit beta O14920 · inhibitor · Inhibitor of nuclear factor kappa B kinase beta subunit inhibitor
- Nuclear factor erythroid 2-related factor 2 Q16236 · inhibitor · Keap1/Nrf2 inhibitor
- Kelch-like ECH-associated protein 1 Q14145 · inhibitor · Keap1/Nrf2 inhibitor
Each resolved target links to its lmmol protein document; action and mechanism are from the bioactivity record.
A document in the lmmol reference corpus — a real compound (PubChem / ChEMBL identity, chemkit-rendered structure) cross-linked to the protein documents it targets. Hover any link to preview its target.