Pemetrexed
SMILES Nc1nc2[nH]cc(CCc3ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)cc3)c2c(=O)[nH]1
Structure
2D skeletal formula · rendered by chemkit from PubChem 2D coordinates.
Pseudo-3D ball-and-stick · chemkit, from PubChem 3D conformer coordinates.
Protein targets · 3 targets
- Dihydrofolate reductase P00374 · inhibitor · Dihydrofolate reductase inhibitor
- Thymidylate synthase P04818 · inhibitor · Thymidylate synthase inhibitor
- Trifunctional purine biosynthetic protein adenosine-3 P22102 · inhibitor · GAR transformylase inhibitor
Each resolved target links to its lmmol protein document; action and mechanism are from the bioactivity record.
A document in the lmmol reference corpus — a real compound (PubChem / ChEMBL identity, chemkit-rendered structure) cross-linked to the protein documents it targets. Hover any link to preview its target.