Lgh-447
SMILES C[C@@H]1C[C@H](N)C[C@H](c2ccncc2NC(=O)c2ccc(F)c(-c3c(F)cccc3F)n2)C1
Structure
2D skeletal formula · rendered by chemkit from PubChem 2D coordinates.
Pseudo-3D ball-and-stick · chemkit, from PubChem 3D conformer coordinates.
Protein targets · 3 targets
- Serine/threonine-protein kinase pim-1 P11309 · inhibitor · Serine/threonine-protein kinase PIM inhibitor
- Serine/threonine-protein kinase pim-2 Q9P1W9 · inhibitor · Serine/threonine-protein kinase PIM inhibitor
- Serine/threonine-protein kinase pim-3 Q86V86 · inhibitor · Serine/threonine-protein kinase PIM inhibitor
Each resolved target links to its lmmol protein document; action and mechanism are from the bioactivity record.
A document in the lmmol reference corpus — a real compound (PubChem / ChEMBL identity, chemkit-rendered structure) cross-linked to the protein documents it targets. Hover any link to preview its target.