Semagacestat
SMILES CC(C)[C@H](O)C(=O)N[C@@H](C)C(=O)N[C@@H]1C(=O)N(C)CCc2ccccc21
Structure
2D skeletal formula · rendered by chemkit from PubChem 2D coordinates.
Pseudo-3D ball-and-stick · chemkit, from PubChem 3D conformer coordinates.
Protein targets · 6 targets
- Gamma-secretase subunit APH-1A Q96BI3 · inhibitor · Gamma-secretase inhibitor
- Gamma-secretase subunit PEN-2 Q9NZ42 · inhibitor · Gamma-secretase inhibitor
- Gamma-secretase subunit APH-1B Q8WW43 · inhibitor · Gamma-secretase inhibitor
- Presenilin-1 P49768 · inhibitor · Gamma-secretase inhibitor
- Nicastrin Q92542 · inhibitor · Gamma-secretase inhibitor
- Presenilin-2 P49810 · inhibitor · Gamma-secretase inhibitor
Each resolved target links to its lmmol protein document; action and mechanism are from the bioactivity record.
A document in the lmmol reference corpus — a real compound (PubChem / ChEMBL identity, chemkit-rendered structure) cross-linked to the protein documents it targets. Hover any link to preview its target.