Rg-4733

InChIKey OJPLJFIFUQPSJR-INIZCTEOSA-N Formula C22H20F5N3O3 PubChem CID 49867930 ChEMBL CHEMBL4297422

SMILES CC(C)(C(=O)NCC(F)(F)C(F)(F)F)C(=O)N[C@@H]1C(=O)Nc2ccccc2-c2ccccc21

Structure

2D skeletal formula · rendered by chemkit from PubChem 2D coordinates.

Pseudo-3D ball-and-stick · chemkit, from PubChem 3D conformer coordinates.

Protein targets · 6 targets

Gamma-secretase subunit APH-1A Q96BI3 · inhibitor · Gamma-secretase inhibitor
Gamma-secretase subunit PEN-2 Q9NZ42 · inhibitor · Gamma-secretase inhibitor
Gamma-secretase subunit APH-1B Q8WW43 · inhibitor · Gamma-secretase inhibitor
Presenilin-1 P49768 · inhibitor · Gamma-secretase inhibitor
Nicastrin Q92542 · inhibitor · Gamma-secretase inhibitor
Presenilin-2 P49810 · inhibitor · Gamma-secretase inhibitor

Each resolved target links to its lmmol protein document; action and mechanism are from the bioactivity record.

A document in the lmmol reference corpus — a real compound (PubChem / ChEMBL identity, chemkit-rendered structure) cross-linked to the protein documents it targets. Hover any link to preview its target.