Nintedanib Esylate
SMILES CCS(=O)(=O)O.COC(=O)c1ccc2c(c1)NC(=O)/C2=C(\Nc1ccc(N(C)C(=O)CN2CCN(C)CC2)cc1)c1ccccc1
Structure
2D skeletal formula · rendered by chemkit from PubChem 2D coordinates.
Protein targets · 9 targets
- Platelet-derived growth factor receptor beta P09619 · inhibitor · Platelet-derived growth factor receptor inhibitor
- Platelet-derived growth factor receptor alpha P16234 · inhibitor · Platelet-derived growth factor receptor inhibitor
- Vascular endothelial growth factor receptor 1 P17948 · inhibitor · Vascular endothelial growth factor receptor inhibitor
- Vascular endothelial growth factor receptor 3 P35916 · inhibitor · Vascular endothelial growth factor receptor inhibitor
- Vascular endothelial growth factor receptor 2 P35968 · inhibitor · Vascular endothelial growth factor receptor inhibitor
- Fibroblast growth factor receptor 3 P22607 · inhibitor · Fibroblast growth factor receptor inhibitor
- Fibroblast growth factor receptor 1 P11362 · inhibitor · Fibroblast growth factor receptor inhibitor
- Fibroblast growth factor receptor 4 P22455 · inhibitor · Fibroblast growth factor receptor inhibitor
- Fibroblast growth factor receptor 2 P21802 · inhibitor · Fibroblast growth factor receptor inhibitor
Each resolved target links to its lmmol protein document; action and mechanism are from the bioactivity record.
A document in the lmmol reference corpus — a real compound (PubChem / ChEMBL identity, chemkit-rendered structure) cross-linked to the protein documents it targets. Hover any link to preview its target.