Nirogacestat Hydrobromide

InChIKey LXEYYZYDWLAIPW-KBVFCZPLSA-N Formula C27H43Br2F2N5O PubChem CID 121513889 ChEMBL CHEMBL4298153

SMILES Br.Br.CCC[C@H](N[C@H]1CCc2cc(F)cc(F)c2C1)C(=O)Nc1cn(C(C)(C)CNCC(C)(C)C)cn1

Structure

2D skeletal formula · rendered by chemkit from PubChem 2D coordinates.

Protein targets · 6 targets

Gamma-secretase subunit APH-1A Q96BI3 · inhibitor · Gamma-secretase inhibitor
Gamma-secretase subunit PEN-2 Q9NZ42 · inhibitor · Gamma-secretase inhibitor
Gamma-secretase subunit APH-1B Q8WW43 · inhibitor · Gamma-secretase inhibitor
Presenilin-1 P49768 · inhibitor · Gamma-secretase inhibitor
Nicastrin Q92542 · inhibitor · Gamma-secretase inhibitor
Presenilin-2 P49810 · inhibitor · Gamma-secretase inhibitor

Each resolved target links to its lmmol protein document; action and mechanism are from the bioactivity record.

A document in the lmmol reference corpus — a real compound (PubChem / ChEMBL identity, chemkit-rendered structure) cross-linked to the protein documents it targets. Hover any link to preview its target.