Lorlatinib
SMILES C[C@H]1Oc2cc(cnc2N)-c2c(nn(C)c2C#N)CN(C)C(=O)c2ccc(F)cc21
Structure
2D skeletal formula · rendered by chemkit from PubChem 2D coordinates.
Pseudo-3D ball-and-stick · chemkit, from PubChem 3D conformer coordinates.
Protein targets · 3 targets
- ALK tyrosine kinase receptor Q9UM73 · inhibitor · ALK tyrosine kinase receptor inhibitor
- ALK tyrosine kinase receptor Q9UM73 · inhibitor · EML4-ALK inhibitor
- Echinoderm microtubule-associated protein-like 4 Q9HC35 · inhibitor · EML4-ALK inhibitor
Each resolved target links to its lmmol protein document; action and mechanism are from the bioactivity record.
A document in the lmmol reference corpus — a real compound (PubChem / ChEMBL identity, chemkit-rendered structure) cross-linked to the protein documents it targets. Hover any link to preview its target.