Altiratinib
SMILES O=C(Nc1cc(Oc2cc(F)c(NC(=O)C3(C(=O)Nc4ccc(F)cc4)CC3)cc2F)ccn1)C1CC1
Structure
2D skeletal formula · rendered by chemkit from PubChem 2D coordinates.
Pseudo-3D ball-and-stick · chemkit, from PubChem 3D conformer coordinates.
Protein targets · 6 targets
- Hepatocyte growth factor receptor P08581 · inhibitor · Hepatocyte growth factor receptor inhibitor
- Angiopoietin-1 receptor Q02763 · inhibitor · Tyrosine-protein kinase TIE-2 inhibitor
- Vascular endothelial growth factor receptor 2 P35968 · inhibitor · Vascular endothelial growth factor receptor 2 inhibitor
- High affinity nerve growth factor receptor P04629 · inhibitor · Neurotrophic tyrosine kinase receptor inhibitor
- BDNF/NT-3 growth factors receptor Q16620 · inhibitor · Neurotrophic tyrosine kinase receptor inhibitor
- NT-3 growth factor receptor Q16288 · inhibitor · Neurotrophic tyrosine kinase receptor inhibitor
Each resolved target links to its lmmol protein document; action and mechanism are from the bioactivity record.
A document in the lmmol reference corpus — a real compound (PubChem / ChEMBL identity, chemkit-rendered structure) cross-linked to the protein documents it targets. Hover any link to preview its target.