Midostaurin
SMILES CO[C@@H]1[C@H](N(C)C(=O)c2ccccc2)C[C@H]2O[C@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4
Structure
2D skeletal formula · rendered by chemkit from PubChem 2D coordinates.
Pseudo-3D ball-and-stick · chemkit, from PubChem 3D conformer coordinates.
Protein targets · 16 targets
- Receptor-type tyrosine-protein kinase FLT3 P36888 · inhibitor · Tyrosine-protein kinase receptor FLT3 inhibitor
- Mast/stem cell growth factor receptor Kit P10721 · inhibitor · Stem cell growth factor receptor inhibitor
- Platelet-derived growth factor receptor beta P09619 · inhibitor · Platelet-derived growth factor receptor inhibitor
- Platelet-derived growth factor receptor alpha P16234 · inhibitor · Platelet-derived growth factor receptor inhibitor
- Serine/threonine-protein kinase D3 O94806 · inhibitor · Protein kinase C (PKC) inhibitor
- Protein kinase C iota type P41743 · inhibitor · Protein kinase C (PKC) inhibitor
- Protein kinase C alpha type P17252 · inhibitor · Protein kinase C (PKC) inhibitor
- Protein kinase C gamma type P05129 · inhibitor · Protein kinase C (PKC) inhibitor
- Protein kinase C delta type Q05655 · inhibitor · Protein kinase C (PKC) inhibitor
- Protein kinase C beta type P05771 · inhibitor · Protein kinase C (PKC) inhibitor
- Protein kinase C zeta type Q05513 · inhibitor · Protein kinase C (PKC) inhibitor
- Protein kinase C epsilon type Q02156 · inhibitor · Protein kinase C (PKC) inhibitor
- Protein kinase C eta type P24723 · inhibitor · Protein kinase C (PKC) inhibitor
- Serine/threonine-protein kinase D1 Q15139 · inhibitor · Protein kinase C (PKC) inhibitor
- Protein kinase C theta type Q04759 · inhibitor · Protein kinase C (PKC) inhibitor
- Vascular endothelial growth factor receptor 2 P35968 · inhibitor · Vascular endothelial growth factor receptor 2 inhibitor
Each resolved target links to its lmmol protein document; action and mechanism are from the bioactivity record.
A document in the lmmol reference corpus — a real compound (PubChem / ChEMBL identity, chemkit-rendered structure) cross-linked to the protein documents it targets. Hover any link to preview its target.