Pacritinib Citrate
SMILES C1=C/COCc2cc(ccc2OCCN2CCCC2)Nc2nccc(n2)-c2cccc(c2)COC/1.O=C(O)CC(O)(CC(=O)O)C(=O)O
Structure
2D skeletal formula · rendered by chemkit from PubChem 2D coordinates.
Protein targets · 4 targets
- Tyrosine-protein kinase JAK2 O60674 · inhibitor · Tyrosine-protein kinase JAK2 inhibitor
- Receptor-type tyrosine-protein kinase FLT3 P36888 · inhibitor · Tyrosine-protein kinase receptor FLT3 inhibitor
- Activin receptor type-1 Q04771 · inhibitor · Activin receptor type-1 inhibitor
- Interleukin-1 receptor-associated kinase 1 P51617 · inhibitor · Interleukin-1 receptor-associated kinase 1 inhibitor
Each resolved target links to its lmmol protein document; action and mechanism are from the bioactivity record.
A document in the lmmol reference corpus — a real compound (PubChem / ChEMBL identity, chemkit-rendered structure) cross-linked to the protein documents it targets. Hover any link to preview its target.