Large ribosomal subunit protein uL16

UniProt Q9HWE2 Organism Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) Gene PA4256, rplP

Also known as: PA4256, rplP

Function

Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.

Classification

Family (Pfam): PF00252 Ribosomal_L16
InterPro: Ribosomal_uL16, Ribosomal_uL16_bact, Ribosomal_uL16_CS, Ribosomal_uL16_dom, Ribosomal_uL16_sf
Functional cluster: Core Ribosomal Proteins (L2/L14/L16)

Experimental structures · PDB · 6

7UNR EM 2.90A
7UNU EM 2.90A
7UNV EM 2.70A
7UNW EM 2.60A
8CD1 EM 3.00A
8RWG EM 2.46A

A predicted model is available from AlphaFold.

Gene Ontology · 5

Drugs targeting this protein · 2

TOBRAMYCIN inhibitor
TOBRAMYCIN SULFATE inhibitor

Related proteins · sequence + function similarity

Literature · 1 cited papers

Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic pathogen. Nature · 2000

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