Large ribosomal subunit protein uL4
Also known as: PA4262, rplD
Function
One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity).
Classification
- Family (Pfam)
- PF00573 Ribosomal_L4
- InterPro
- Ribosomal_uL4, Ribosomal_uL4-like, Ribosomal_uL4_dom_sf
- Functional cluster
- Large-Subunit Ribosomal Proteins (L4/L20/L35)
Experimental structures · PDB · 6
A predicted model is available from AlphaFold.
Gene Ontology · 5
Drugs targeting this protein · 2
- TOBRAMYCIN inhibitor
- TOBRAMYCIN SULFATE inhibitor
Related proteins · sequence + function similarity
- Large ribosomal subunit protein uL4 1.00
- Large ribosomal subunit protein uL4 1.00
- Large ribosomal subunit protein uL4 0.98
- Large ribosomal subunit protein uL4 0.98
- Large ribosomal subunit protein uL4 0.98
- Large ribosomal subunit protein uL4 0.98
- Large ribosomal subunit protein uL4 0.98
- Large ribosomal subunit protein uL4 0.98
- Large ribosomal subunit protein uL4 0.98
- Large ribosomal subunit protein uL4 0.98
- Large ribosomal subunit protein uL4 0.98
- Large ribosomal subunit protein uL4 0.98
Co-cited proteins · studied together in the literature
- Large ribosomal subunit protein uL4 1 shared papers
- Small ribosomal subunit protein uS10 1 shared papers
- Bacterioferritin-associated ferredoxin 1 shared papers
- Large ribosomal subunit protein uL4 1 shared papers
- Bacterioferritin 1 shared papers
- Large ribosomal subunit protein uL4 1 shared papers
- Large ribosomal subunit protein uL4 1 shared papers
- Large ribosomal subunit protein uL4 1 shared papers
Literature · 2 cited papers
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