Large ribosomal subunit protein uL3
Also known as: M5005_Spy0044, SPy_0049, rplC
Function
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
Classification
- Family (Pfam)
- PF00297 Ribosomal_L3
- InterPro
- Ribosomal_uL3, Ribosomal_uL3_bact_org, Ribosomal_uL3_CS, Transl_B-barrel_sf
- Functional cluster
- Large Ribosomal Subunit Proteins
Gene Ontology · 4
Drugs targeting this protein · 1
- RETAPAMULIN inhibitor
Related proteins · sequence + function similarity
- Large ribosomal subunit protein uL3 1.00
- Large ribosomal subunit protein uL3 1.00
- Large ribosomal subunit protein uL3 1.00
- Large ribosomal subunit protein uL3 1.00
- Large ribosomal subunit protein uL3 1.00
- Large ribosomal subunit protein uL3 1.00
- Large ribosomal subunit protein uL3 1.00
- Large ribosomal subunit protein uL3 1.00
- Large ribosomal subunit protein uL3 1.00
- Large ribosomal subunit protein uL3 1.00
- Large ribosomal subunit protein uL3 1.00
- Large ribosomal subunit protein uL3 1.00
Literature · 2 cited papers
- Evolutionary origin and emergence of a highly successful clone of serotype M1 group A Streptococcus involved multiple horizontal gene transfer events. J. Infect. Dis. · 2005
- Complete genome sequence of an M1 strain of Streptococcus pyogenes. Proc. Natl. Acad. Sci. U.S.A. · 2001
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