Large ribosomal subunit protein uL3

UniProt Q8CWV8 Organism Streptococcus pneumoniae (strain ATCC BAA-255 / R6) Gene rplC, spr0188

Also known as: rplC, spr0188

Function

One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.

Classification

Family (Pfam): PF00297 Ribosomal_L3
InterPro: Ribosomal_uL3, Ribosomal_uL3_bact_org, Ribosomal_uL3_CS, Transl_B-barrel_sf
Functional cluster: Large Ribosomal Subunit Proteins

Gene Ontology · 4

GO:0022625 cytosolic large ribosomal subunit
GO:0019843 rRNA binding
GO:0003735 structural constituent of ribosome
GO:0006412 translation

Drugs targeting this protein · 2

LINCOMYCIN HYDROCHLORIDE inhibitor
TROLEANDOMYCIN inhibitor

Related proteins · sequence + function similarity

Large ribosomal subunit protein uL3 1.00
Large ribosomal subunit protein uL3 1.00
Large ribosomal subunit protein uL3 1.00
Large ribosomal subunit protein uL3 1.00
Large ribosomal subunit protein uL3 1.00
Large ribosomal subunit protein uL3 1.00
Large ribosomal subunit protein uL3 1.00
Large ribosomal subunit protein uL3 1.00
Large ribosomal subunit protein uL3 1.00
Large ribosomal subunit protein uL3 1.00
Large ribosomal subunit protein uL3 0.99
Large ribosomal subunit protein uL3 0.99

Literature · 1 cited papers

Genome of the bacterium Streptococcus pneumoniae strain R6. J. Bacteriol. · 2001

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