Small ribosomal subunit protein uS7

Function

One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.

Classification

Family (Pfam)

PF00177 Ribosomal_S7

InterPro

Ribosomal_uS7, Ribosomal_uS7_bact_org, Ribosomal_uS7_CS, Ribosomal_uS7_dom, Ribosomal_uS7_dom_sf

Functional cluster

Core Ribosomal Proteins (L2/L14/L16)

Gene Ontology · 7

• GO:0022627 cytosolic small ribosomal subunit
• GO:0005840 ribosome
• GO:0003729 mRNA binding
• GO:0019843 rRNA binding
• GO:0003735 structural constituent of ribosome
• GO:0000049 tRNA binding
• GO:0006412 translation

Drugs targeting this protein · 2

• LINCOMYCIN HYDROCHLORIDE inhibitor
• TROLEANDOMYCIN inhibitor

Related proteins · sequence + function similarity

• Small ribosomal subunit protein uS7 1.00
• Small ribosomal subunit protein uS7 1.00
• Small ribosomal subunit protein uS7 1.00
• Small ribosomal subunit protein uS7 1.00
• Small ribosomal subunit protein uS7 1.00
• Small ribosomal subunit protein uS7 1.00
• Small ribosomal subunit protein uS7 1.00
• Small ribosomal subunit protein uS7 1.00
• Small ribosomal subunit protein uS7 0.99
• Small ribosomal subunit protein uS7 0.99
• Small ribosomal subunit protein uS7 0.99
• Small ribosomal subunit protein uS7 0.98

Literature · 1 cited papers

• Genome of the bacterium Streptococcus pneumoniae strain R6. J. Bacteriol. · 2001