GPI-anchored wall transfer protein 1

Function

Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor.

Classification

Family (Pfam)

PF06423 GWT1

InterPro

PIGW/GWT1

Functional cluster

Nuclear Transport & RNA-Processing Proteins

Gene Ontology · 4

• GO:0005783 endoplasmic reticulum
• GO:0005789 endoplasmic reticulum membrane
• GO:0032216 glucosaminyl-phosphatidylinositol O-acyltransferase activity
• GO:0006506 GPI anchor biosynthetic process

Drugs targeting this protein · 1

• FOSMANOGEPIX inhibitor

Related proteins · sequence + function similarity

• GPI-anchored wall transfer protein 1 0.96
• GPI-anchored wall transfer protein 1 0.95
• GPI-anchored wall transfer protein 1 0.94
• GPI-anchored wall transfer protein 1 0.84
• GPI-anchored wall transfer protein 1 0.82
• GPI-anchored wall transfer protein 1 0.82
• Phosphatidylinositol-glycan biosynthesis class W protein 0.81
• GPI-anchored wall transfer protein 1 0.81
• GPI-anchored wall transfer protein 1 0.78
• GPI-anchored wall transfer protein 1 0.78
• GPI-anchored wall transfer protein 1 0.77
• GPI-anchored wall transfer protein 1 0.77

Co-cited proteins · studied together in the literature

• GPI-anchored wall transfer protein 1 1 shared papers
• GPI-anchored wall transfer protein 1 1 shared papers

Literature · 4 cited papers

• Assembly of a phased diploid Candida albicans genome facilitates allele-specific measurements and provides a simple model for repeat and indel structure. Genome Biol. · 2013
• Assembly of the Candida albicans genome into sixteen supercontigs aligned on the eight chromosomes. Genome Biol. · 2007
• The diploid genome sequence of Candida albicans. Proc. Natl. Acad. Sci. U.S.A. · 2004
• Medicinal genetics approach towards identifying the molecular target of a novel inhibitor of fungal cell wall assembly. Mol. Microbiol. · 2003