lmmol · Proteins

Enoyl-[acyl-carrier-protein] reductase [NADPH] FabI

UniProt Q6GI75 Organism Staphylococcus aureus (strain MRSA252) Gene SAR0978, fabI EC 1.3.1.39

Also known as: SAR0978, fabI

Function

Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP). Involved in the elongation cycle of fatty acid which are used in the lipid metabolism (By similarity).

Classification

Family (Pfam)
PF13561 adh_short_C2
InterPro
Enoyl-ACP_Rdtase_NADH, NAD(P)-bd_dom_sf, SDR_fam
Functional cluster
Phosphoribosyltransferases & related

Experimental structures · PDB · 4

A predicted model is available from AlphaFold.

Gene Ontology · 5

Drugs targeting this protein · 3

Related proteins · sequence + function similarity

Literature · 2 cited papers

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