Small ribosomal subunit protein uS13

UniProt Q2FW30 Organism Staphylococcus aureus (strain NCTC 8325 / PS 47) Gene SAOUHSC_02487, rpsM

Also known as: SAOUHSC_02487, rpsM

Function

Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.

Classification

Family (Pfam): PF00416 Ribosomal_S13
InterPro: Rbsml_uS13_C, Ribosomal_uS13, Ribosomal_uS13-like_H2TH, Ribosomal_uS13_bact, Ribosomal_uS13_CS
Functional cluster: Ribosomal S13 & Maturase Proteins

Experimental structures · PDB · 17

5LI0 EM 3.80A
5ND8 EM 3.70A
5ND9 EM 3.70A
5TCU EM 3.90A
6YEF EM 3.20A
7BGE EM 3.60A
7KWG EM 3.75A
7NHL EM 3.10A
7NHM EM 3.10A
8BH6 EM 3.70A
8BH7 EM 4.23A
8BYV EM 2.89A
… and 5 more

A predicted model is available from AlphaFold.

Gene Ontology · 6

Drugs targeting this protein · 1

RETAPAMULIN inhibitor

Related proteins · sequence + function similarity

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