Large ribosomal subunit protein uL6
Also known as: SAOUHSC_02496, rplF
Function
This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.
Classification
- Family (Pfam)
- PF00347 Ribosomal_L6
- InterPro
- Ribosomal_uL6-like, Ribosomal_uL6-like_a/b-dom_sf, Ribosomal_uL6_a/b-dom, Ribosomal_uL6_bact, Ribosomal_uL6_CS
- Functional cluster
- Globins & Ribosomal Protein L6
Experimental structures · PDB · 22
- 4WCE X-ray 3.53A
- 4WF9 X-ray 3.43A
- 4WFA X-ray 3.39A
- 4WFB X-ray 3.43A
- 5HKV X-ray 3.66A
- 5HL7 X-ray 3.55A
- 5LI0 EM 3.80A
- 5ND8 EM 3.70A
- 5ND9 EM 3.70A
- 5NRG X-ray 3.44A
- 5TCU EM 3.90A
- 6HMA EM 2.65A
- … and 10 more
A predicted model is available from AlphaFold.
Gene Ontology · 4
Drugs targeting this protein · 1
- RETAPAMULIN inhibitor
Related proteins · sequence + function similarity
- Large ribosomal subunit protein uL6 1.00
- Large ribosomal subunit protein uL6 1.00
- Large ribosomal subunit protein uL6 1.00
- Large ribosomal subunit protein uL6 1.00
- Large ribosomal subunit protein uL6 1.00
- Large ribosomal subunit protein uL6 1.00
- Large ribosomal subunit protein uL6 1.00
- Large ribosomal subunit protein uL6 1.00
- Large ribosomal subunit protein uL6 1.00
- Large ribosomal subunit protein uL6 1.00
- Large ribosomal subunit protein uL6 1.00
- Large ribosomal subunit protein uL6 1.00
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