Large ribosomal subunit protein uL24
Also known as: SAOUHSC_02501, rplX
Function
One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
Classification
- Family (Pfam)
- PF00467 KOW, PF17136 ribosomal_L24
- InterPro
- KOW, Rib_uL2_dom2, Ribosomal_uL24, Ribosomal_uL24_C, Ribosomal_uL24_CS, Ribosomal_uL24_KOW, Translation_prot_SH3-like_sf
- Functional cluster
- Ribosomal Proteins (S16/S17/L24/L30)
Experimental structures · PDB · 31
- 4WCE X-ray 3.53A
- 4WF9 X-ray 3.43A
- 4WFA X-ray 3.39A
- 4WFB X-ray 3.43A
- 5HKV X-ray 3.66A
- 5HL7 X-ray 3.55A
- 5LI0 EM 3.80A
- 5ND8 EM 3.70A
- 5ND9 EM 3.70A
- 5NRG X-ray 3.44A
- 5TCU EM 3.90A
- 6DDD EM 3.10A
- … and 19 more
A predicted model is available from AlphaFold.
Gene Ontology · 4
Drugs targeting this protein · 1
- RETAPAMULIN inhibitor
Related proteins · sequence + function similarity
- Large ribosomal subunit protein uL24 1.00
- Large ribosomal subunit protein uL24 1.00
- Large ribosomal subunit protein uL24 1.00
- Large ribosomal subunit protein uL24 1.00
- Large ribosomal subunit protein uL24 1.00
- Large ribosomal subunit protein uL24 1.00
- Large ribosomal subunit protein uL24 1.00
- Large ribosomal subunit protein uL24 1.00
- Large ribosomal subunit protein uL24 1.00
- Large ribosomal subunit protein uL24 1.00
- Large ribosomal subunit protein uL24 1.00
- Large ribosomal subunit protein uL24 1.00
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