Large ribosomal subunit protein uL23
Also known as: SAOUHSC_02510, rplW
Function
One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.
Classification
- Family (Pfam)
- PF00276 Ribosomal_L23
- InterPro
- Nucleotide-bd_a/b_plait_sf, Ribosomal_uL23-like, Ribosomal_uL23/eL15/eS24_sf
- Functional cluster
- Small/Large Ribosomal Subunit Proteins
Experimental structures · PDB · 31
- 4WCE X-ray 3.53A
- 4WF9 X-ray 3.43A
- 4WFA X-ray 3.39A
- 4WFB X-ray 3.43A
- 5HKV X-ray 3.66A
- 5HL7 X-ray 3.55A
- 5LI0 EM 3.80A
- 5ND8 EM 3.70A
- 5ND9 EM 3.70A
- 5NRG X-ray 3.44A
- 5TCU EM 3.90A
- 6DDD EM 3.10A
- … and 19 more
A predicted model is available from AlphaFold.
Gene Ontology · 4
Drugs targeting this protein · 1
- RETAPAMULIN inhibitor
Related proteins · sequence + function similarity
- Large ribosomal subunit protein uL23 1.00
- Large ribosomal subunit protein uL23 1.00
- Large ribosomal subunit protein uL23 1.00
- Large ribosomal subunit protein uL23 1.00
- Large ribosomal subunit protein uL23 1.00
- Large ribosomal subunit protein uL23 1.00
- Large ribosomal subunit protein uL23 1.00
- Large ribosomal subunit protein uL23 1.00
- Large ribosomal subunit protein uL23 1.00
- Large ribosomal subunit protein uL23 1.00
- Large ribosomal subunit protein uL23 1.00
- Large ribosomal subunit protein uL23 0.99
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