Large ribosomal subunit protein uL3
Also known as: SAOUHSC_02512, rplC
Function
One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.
Classification
- Family (Pfam)
- PF00297 Ribosomal_L3
- InterPro
- Ribosomal_uL3, Ribosomal_uL3_bact_org, Ribosomal_uL3_CS, Transl_B-barrel_sf
- Functional cluster
- Large Ribosomal Subunit Proteins
Experimental structures · PDB · 30
- 4WF9 X-ray 3.43A
- 4WFA X-ray 3.39A
- 4WFB X-ray 3.43A
- 5HKV X-ray 3.66A
- 5HL7 X-ray 3.55A
- 5LI0 EM 3.80A
- 5ND8 EM 3.70A
- 5ND9 EM 3.70A
- 5NRG X-ray 3.44A
- 5TCU EM 3.90A
- 6DDD EM 3.10A
- 6DDG EM 3.10A
- … and 18 more
A predicted model is available from AlphaFold.
Gene Ontology · 4
Drugs targeting this protein · 1
- RETAPAMULIN inhibitor
Related proteins · sequence + function similarity
- Large ribosomal subunit protein uL3 1.00
- Large ribosomal subunit protein uL3 1.00
- Large ribosomal subunit protein uL3 1.00
- Large ribosomal subunit protein uL3 1.00
- Large ribosomal subunit protein uL3 1.00
- Large ribosomal subunit protein uL3 1.00
- Large ribosomal subunit protein uL3 1.00
- Large ribosomal subunit protein uL3 1.00
- Large ribosomal subunit protein uL3 1.00
- Large ribosomal subunit protein uL3 1.00
- Large ribosomal subunit protein uL3 0.98
- Large ribosomal subunit protein uL3 0.98
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