DNA-directed RNA polymerase subunit alpha
Also known as: CD630_00980, rpoA
Function
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
Classification
- Family (Pfam)
- PF01000 RNA_pol_A_bac, PF03118 RNA_pol_A_CTD, PF01193 RNA_pol_L
- InterPro
- DNA-dir_RNA_pol_insert, DNA-dir_RNA_pol_RpoA/D/Rpb3, DNA-dir_RpoA, RBP11-like, RNAP_asu_C, RNApol_insert_sf
- Functional cluster
- AAA+ ATPases & Chaperones
Experimental structures · PDB · 1
- 7L7B EM 3.26A
A predicted model is available from AlphaFold.
Gene Ontology · 6
Drugs targeting this protein · 1
- FIDAXOMICIN inhibitor
Related proteins · sequence + function similarity
- DNA-directed RNA polymerase subunit alpha 0.96
- DNA-directed RNA polymerase subunit alpha 0.94
- DNA-directed RNA polymerase subunit alpha 0.94
- DNA-directed RNA polymerase subunit alpha 0.94
- DNA-directed RNA polymerase subunit alpha 0.93
- DNA-directed RNA polymerase subunit alpha 0.93
- DNA-directed RNA polymerase subunit alpha 0.93
- DNA-directed RNA polymerase subunit alpha 0.93
- DNA-directed RNA polymerase subunit alpha 0.92
- DNA-directed RNA polymerase subunit alpha 0.92
- DNA-directed RNA polymerase subunit alpha 0.92
- DNA-directed RNA polymerase subunit alpha 0.92
Literature · 1 cited papers
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