ATP synthase subunit b-delta
Also known as: Rv1307, atpF, atpFH, atpH
Function
F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity).
Classification
- Family (Pfam)
- PF00430 ATP-synt_B, PF00213 OSCP
- InterPro
- ATP_synth_B-like_membr_sf, ATP_synth_b/b'su_bac/chlpt, ATP_synth_F0_bsu_bac, ATP_synth_OSCP/delta_N_sf, ATPase_OSCP/dsu
- Functional cluster
- Peptide Chain Release Factors & related
Experimental structures · PDB · 3
A predicted model is available from AlphaFold.
Gene Ontology · 5
Drugs targeting this protein · 1
- BEDAQUILINE FUMARATE inhibitor
Related proteins · sequence + function similarity
- ATP synthase subunit b-delta 1.00
- ATP synthase subunit b-delta 1.00
- ATP synthase subunit b-delta 1.00
- ATP synthase subunit b-delta 1.00
- ATP synthase subunit b-delta 0.97
- ATP synthase subunit b-delta 0.97
- ATP synthase subunit b-delta 0.97
- ATP synthase subunit b-delta 0.97
- ATP synthase subunit b-delta 0.97
- ATP synthase subunit b-delta 0.96
- ATP synthase subunit b-delta 0.94
- ATP synthase subunit b-delta 0.94
Literature · 3 cited papers
- Proteogenomic analysis of Mycobacterium tuberculosis by high resolution mass spectrometry. Mol. Cell. Proteomics · 2011
- targetTB: a target identification pipeline for Mycobacterium tuberculosis through an interactome, reactome and genome-scale structural analysis. BMC Syst. Biol. · 2008
- Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Nature · 1998
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