ATP synthase gamma chain
Also known as: Rv1309, atpG
Function
Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.
Classification
- Family (Pfam)
- PF00231 ATP-synt
- InterPro
- ATP_synth_F1_ATPase_gsu, ATP_synth_F1_gsu, ATP_synth_F1_gsu_CS
- Functional cluster
- ATP Synthase Gamma Subunit & related
Experimental structures · PDB · 3
A predicted model is available from AlphaFold.
Gene Ontology · 7
- GO:0009274 peptidoglycan-based cell wall
- GO:0005886 plasma membrane
- GO:0045259 proton-transporting ATP synthase complex
- GO:0005524 ATP binding
- GO:0046933 proton-transporting ATP synthase activity, rotational mechanism
- GO:0015986 proton motive force-driven ATP synthesis
- GO:0042777 proton motive force-driven plasma membrane ATP synthesis
Drugs targeting this protein · 1
- BEDAQUILINE FUMARATE inhibitor
Related proteins · sequence + function similarity
- ATP synthase gamma chain 1.00
- ATP synthase gamma chain 1.00
- ATP synthase gamma chain 1.00
- ATP synthase gamma chain 1.00
- ATP synthase gamma chain 0.98
- ATP synthase gamma chain 0.98
- ATP synthase gamma chain 0.97
- ATP synthase gamma chain 0.97
- ATP synthase gamma chain 0.96
- ATP synthase gamma chain 0.96
- ATP synthase gamma chain 0.96
- ATP synthase gamma chain 0.95
Literature · 2 cited papers
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