Large ribosomal subunit protein bL31

Function

Binds 23S rRNA.

Classification

Family (Pfam)

PF01197 Ribosomal_L31

InterPro

Ribosomal_bL28/bL31-like_sf, Ribosomal_bL31, Ribosomal_bL31_A, Ribosomal_bL31_sf

Functional cluster

Small-Subunit Ribosomal Proteins

Experimental structures · PDB · 11

• 5V7Q EM 3.70A
• 5V93 EM 4.00A
• 7KGB EM 2.70A
• 7MSC EM 2.97A
• 7MSH EM 3.23A
• 7MSM EM 2.79A
• 7MSZ EM 3.10A
• 7MT2 EM 2.76A
• 7MT3 EM 2.80A
• 7MT7 EM 2.71A
• 7SFR EM 2.60A

A predicted model is available from AlphaFold.

Gene Ontology · 6

• GO:1990904 ribonucleoprotein complex
• GO:0005840 ribosome
• GO:0046872 metal ion binding
• GO:0019843 rRNA binding
• GO:0003735 structural constituent of ribosome
• GO:0006412 translation

Drugs targeting this protein · 4

• CAPREOMYCIN SULFATE inhibitor
• SUTEZOLID inhibitor
• VIOMYCIN SULFATE inhibitor
• PYRAZINAMIDE inhibitor

Related proteins · sequence + function similarity

• Large ribosomal subunit protein bL31 1.00
• Large ribosomal subunit protein bL31 1.00
• Large ribosomal subunit protein bL31 1.00
• Large ribosomal subunit protein bL31 1.00
• Large ribosomal subunit protein bL31 0.93
• Large ribosomal subunit protein bL31 0.93
• Large ribosomal subunit protein bL31 0.93
• Large ribosomal subunit protein bL31 0.93
• Large ribosomal subunit protein bL31 0.93
• Large ribosomal subunit protein bL31 0.92
• Large ribosomal subunit protein bL31 0.92
• Large ribosomal subunit protein bL31 0.91

Literature · 4 cited papers

• Interplay between an ATP-binding cassette F protein and the ribosome from Mycobacterium tuberculosis. Nat. Commun. · 2022
• Structural insights into species-specific features of the ribosome from the human pathogen Mycobacterium tuberculosis. Nucleic Acids Res. · 2017
• Proteogenomic analysis of Mycobacterium tuberculosis by high resolution mass spectrometry. Mol. Cell. Proteomics · 2011
• Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Nature · 1998