Small ribosomal subunit protein uS4

UniProt P66567 Organism Streptococcus pyogenes serotype M1 Gene M5005_Spy1831, SPy_2178, rpsD

Also known as: M5005_Spy1831, SPy_2178, rpsD

Function

One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.

Classification

Family (Pfam): PF00163 Ribosomal_S4, PF01479 S4
InterPro: Ribosomal_uS4, Ribosomal_uS4_bact, Ribosomal_uS4_CS, Ribosomal_uS4_N, S4_RNA-bd, S4_RNA-bd_sf
Functional cluster: Photosystem Reaction-Center Proteins

Gene Ontology · 5

Drugs targeting this protein · 1

RETAPAMULIN inhibitor

Related proteins · sequence + function similarity

Literature · 2 cited papers

Evolutionary origin and emergence of a highly successful clone of serotype M1 group A Streptococcus involved multiple horizontal gene transfer events. J. Infect. Dis. · 2005
Complete genome sequence of an M1 strain of Streptococcus pyogenes. Proc. Natl. Acad. Sci. U.S.A. · 2001

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